Cholinergic and anti-cholinergic

Question 1

Which of the following drugs blocks the action of acetylcholine at muscarinic receptors?
A) Atropine
B) Nicotine
C) Donepezil
D) Physostigmine

Answer 1

A) Atropine

Question 2

Cholinergic agonists primarily mimic the effects of:
A) Acetylcholine
B) Dopamine
C) Serotonin
D) Norepinephrine

Answer 2

A) Acetylcholine

Question 3

Which of the following drugs is a reversible acetylcholinesterase inhibitor?
A) Atropine
B) Pralidoxime
C) Scopolamine
D) Tolterodine

Answer 3

B) Pralidoxime

Question 4

Which of the following statements regarding cholinergic agonists is true?
A) They decrease gastrointestinal motility
B) They increase heart rate
C) They decrease bronchial secretions
D) They cause pupil constriction

Answer 4

Answer: D) They cause pupil constriction

Question 5

The primary clinical use of atropine is:
A) To treat urinary retention
B) To treat Alzheimer’s disease
C) To treat bradycardia
D) To treat depression

Answer 5

Answer: C) To treat bradycardia

Question 6

Which of the following is a common adverse effect of anticholinergic drugs?
A) Diarrhea
B) Bradycardia
C) Miosis
D) Dry mouth

Answer 6

Answer: D) Dry mouth

Question 7

Which of the following is an example of a direct-acting cholinergic agonist?
A) Donepezil
B) Scopolamine
C) Neostigmine
D) Bethanechol

Answer 7

Answer: D) Bethanechol

Question 8

The antidote for anticholinergic toxicity is:
A) Physostigmine
B) Atropine
C) Pralidoxime
D) Tolterodine

Answer 8

A) Physostigmine

Question 9

Which of the following cholinergic agonists is used to treat myasthenia gravis?
A) Atropine
B) Neostigmine
C) Glycopyrrolate
D) Oxybutynin

Answer 9

B) Neostigmine

Question 10

Which of the following drugs is a cholinergic agonist used in the treatment of xerostomia?
A) Atropine
B) Pilocarpine
C) Tolterodine
D) Physostigmine

Answer 10

B) Pilocarpine

Question 11

Which of the following drugs is a cholinergic agonist used in the treatment of urinary retention?
A) Atropine
B) Neostigmine
C) Bethanechol
D) Scopolamine

Answer 11

C) Bethanechol

Question 12

Which of the following drugs is a cholinesterase inhibitor used in the treatment of myasthenia gravis?
A) Ipratropium
B) Rivastigmine
C) Pyridostigmine
D) Tolterodine

Answer 12

Answer: C) Pyridostigmine

Question 13

Which of the following cholinergic agonists is used in the treatment of Alzheimer’s disease?
A) Donepezil
B) Neostigmine
C) Atropine
D) Scopolamine

Answer 13

A) Donepezil

Question 14

Which of the following drugs is a cholinesterase inhibitor used in the treatment of myasthenia gravis?
A) Ipratropium
B) Rivastigmine
C) Pyridostigmine
D) Tolterodine

Answer 14

C) Pyridostigmine

Question 15

What are the major contraindications of direct cholinergic agonists

Answer 15

Asthma and peptic ulcers

Question 16

What are some reversible indirect cholinergic agonist

Answer 16

Nicotine, neostigmine, physostigmine

Question 17

What are some irreversible indirect cholinergic agonist

Answer 17

Sarin, malathion, parathion

Question 18

What drug can be used to reverse the effect of non-depolarising NMBA?

Answer 18

Neostigmine- anticholinesterase

Question 19

Which muscarinic receptor has a sympathetic cholinergic receptor ?

Answer 19

M3 in secretory glands (Eccrine glands)

Question 20

What is the drug effect of bethanechol?

Answer 20

It decreases detrusor tone, and reduce outlet resistance of the internal sphincter, increase GI motility and secretion.

Question 21

What are the side effects of varenicline?

Answer 21

May be associated with psychiatric symptoms such as suicidal ideation

Question 22

What are the antidotes for organophosphates

Answer 22

Pralidoxime and atropine

Question 23

What is the effect of parasympatholytics on the pupil of the eye?

Answer 23

Mydriasis ( dilation)
Because is parasympatholytic (anti cholinergic effect)