Chp 19 - Diuretics Flashcards

1
Q

Diuretic

A

Substance that INCREASES urine flow

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2
Q

Polyuria

A

Increased urine output by excessive urination

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3
Q

Oliguria

A

Decreased urine flow

Sign of renal failure

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4
Q

Carbonic Anhydrase Inhibitors

CAI

A

Block reabsorption of Na and HCO3 for PROXIMAL TUBULE

  • glaucoma
  • lower HCO3
  • altitude sickness
  • metabolic alkalosis
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5
Q

Acetazolamide

A

CAI

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6
Q

Dichlorphenamide

A

CAI

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7
Q

Methazolamine

A

CAI

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8
Q

Osmotic Diuretics

A

Reduce absorption of H2O and NaCl in the PROXIMAL TUBULE so increases the excretion of them

Decreases ICP, IOP
For bronchial challenge
Management of traumatic brain injury

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9
Q

Mannitol

A

OD

Tx cerebral edema

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10
Q

Glycerol

A

OD

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11
Q

Urea

A

OD

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12
Q

Loop Diuretics

A

Block reabsorption of Na, K, Cl in ASCENDING loop of Henle

Need to have electrolytes monitored
May cause vasodilation

  • fluid overload
  • CHF
  • edema
  • hepatic ascites
  • hypercalcemia
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13
Q

Lasix (furosemide)

A

LD
Less toxic
Peds

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14
Q

Bumex (bumetanide)

A

LD

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15
Q

Demadex (torsemide)

A

LD

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16
Q

“High ceiling” diuretics

A

Loop diuretics
High diuretic potential
Interfere w the reabsorption of K, Mg,Ca

17
Q

Thiazide Diuretics

A

Inhibit NaCl reabsorption in the early DISTAL TUBULE

  • first line for Hypertension
  • mild ❤️ failure

Given in combination w loop for severe edema but can cause hyperglycemia

18
Q

Clorothiazide

A

TD

19
Q

Metolazone

A

Thiozide-like diuretic

Given w loop

20
Q

Indapamide and Chlorthalidone

A

Thiazide-like diuretic

21
Q

K- Sparing Diuretics

A

Exert their action at the COLLECTING DUCTS

  • prevent hypokalemia caused by loop/thiazide
  • CONN’S SYNDROME
22
Q

Amiloride and Triamterene

A

Act by blocking Na channels in luminal membrane of CT

23
Q

Spironolactone (Aldactone)

A

Competitive aldosterone inhibitor

KSD

24
Q

Normal urine output

A

30-60mL/hr