Chp 33 Rheumatoid Arthritis Flashcards Preview

NCLEX Pharmacology > Chp 33 Rheumatoid Arthritis > Flashcards

Flashcards in Chp 33 Rheumatoid Arthritis Deck (9)
Loading flashcards...
1
Q

What are some Major Nonbiologic DMARDs? (4)

A
  • immunosuppressant med; methotrexate
  • antimalarial agents: hydroxychloroquine
  • Anti-inflammatory med; sulfasalazine
  • tetracycline antibiotic: minocycline
2
Q

What are some Major Biologic DMARDs?

A
  • Etanercept
  • Infliximab
  • Adalimumab
  • Rituximab
  • Abatacept
3
Q

Pharmacological Action of DMARDs?

A

slows joint degeneration and progression of RA

4
Q

Pharmacological Action of Glucocorticoids?

A

Symptomatic relief of inflammation and pain

5
Q

Pharmacological Action of NSAIDs?

A

Provides rapid, symptomatic relief of inflammation and pain.

6
Q

What are complications of methotrexate?

A

it’s cytotoxic

  • risk of infection
  • hepatic fibrosis
  • bone marrow suppression
  • ulcerative stomatitis
  • fetal death/congenital abnormalities
7
Q

What are adverse effects of hydroxychloroquine?

A

Retinal damage

8
Q

What is methotrexate contraindicated with?

A

Pt with liver failure, alcoholism, or blood dyscrasias

9
Q

Contraindications of etanercept?

A

Pt that have malignancies, active infection, hematologic disorder, or during lactation