chp 8 carbo Flashcards
(31 cards)
fructose 1-6 biphosphate is turned on by ?
citrate
fructose 1-6 biphosphate is turned off by ?
AMP, F-2,6-bisphosphate
Pyruvate carboxylase is turned on by ?
Acetyl-CoA
Phosphofructokinase (PFK) tuned on by ?
AMP, F-2,6-bisphosphate
Phosphofructokinase (PFK) turned off by ?
ATP, Citrate
Pyruvate kinase turned on by ?
F-1,6-BP
Pyruvate kinase turned off by ?
ATP, Acetyl-CoA, cAMP
wt does glucagon do
?
- helps the liver make glucose
- turns off glycolyisis enzymes
-turns on gluconeogensis enzymes
wt does insulin do ?
-stops glucose production
-pushes glucose into cells
-turns on glycolysis enzymes
wt does the cortisol do ?
boosts glucose production over time
wts a cortisol ?
stress hormone
βοΈ What decides if your body does glycolysis or gluconeogenesis?
π After eating = Insulin wins β use glucose (glycolysis)
π₯© After fasting = Glucagon wins β make glucose (gluconeogenesis)
𧨠High AMP = no energy β do glycolysis
π Low AMP = lots of energy β do gluconeogenesis
PPP has another name
Hexose Monophosphate Shunt (HMP shunt)
PPP helps make glucose where
dark (not during sunlight).
Red blood cells and liver cells (hepatocytes) = use PPP a lot because they need a lot of ?
NADPH
do we need NADPH in making fats
yes , thats why adipose and liver cells love ppp
do muscle cells make fat ?
dont make fat So they donβt need NADPH much
β So PPP is not active there
Activates it (we need NADPH to reduce it) who ?
GSSG (oxidized glutathione)
NADPH is needed for:
Making fats (lipogenesis)
Making cholesterol
Defending against oxidative stress
G6PD is inhibited by
NADPH
G6PDβ Stimulated by
oxidized glutathione (GSSG)
Fructose is found in ?
fruit
honey
sweets and soda
wt is glycpgen ?
storage form of glucose when blood glucose is high ur body stores glucose as glycogen mainly in the liver and muscle
wt does glycogensis do ?
makes glucose