Chpt 26 PATHOPHYSIOLOGY OF BURN INJURY Flashcards Preview

Med Surg 3 > Chpt 26 PATHOPHYSIOLOGY OF BURN INJURY > Flashcards

Flashcards in Chpt 26 PATHOPHYSIOLOGY OF BURN INJURY Deck (16):
1

What is burns path

Burns are complex injuries with loss of tissue integrity that cause patients to develop many physiologic, metabolic, and psychological changes.

2

The tissue destruction caused by a burn injury affects

fluid and electrolyte balance, and leads to local and systemic problems, including fluid and protein losses, sepsis, and changes in metabolic, endocrine, respiratory, cardiac, hematologic, and immune functioning.

3

superficial-thickness wounds

the epidermis is the only part of the skin that is injured.

4

partial-thickness wound

involves the entire epidermis and varying depths of the dermis

5

full-thickness wound

destruction of the entire epidermis and dermis, leaving no true skin cells to repopulate; therefore, skin will not regrow.

6

After a burn injury, there is a massive fluid loss through

evaporation.

7

Circulatory disruption

Blood vessels to the burned skin are occluded, and blood flow is reduced or stopped.
• Damaged macrophages within the tissues release chemical mediators that cause blood vessel constriction.
• Blood vessel thrombosis may occur, causing necrosis

8

fluid shift occurs after initial vasoconstriction

dilating and leaking fluids into the interstitial space

9

continuous leak of plasma fluids and proteins from the vascular space into the interstitial space, which

decreases blood volume and blood pressure.

10

Profound disruptions of fluid and electrolyte balance and acid-base balance

imbalances include hypovolemia, metabolic acidosis, hyperkalemia, and hyponatremia.

11

Fluid remobilization starts about

24 hours after injury, when the capillary leak stops and capillary integrity is restored.

12

diuretic stage begins at about

48 to 72 hours after the burn injury as capillary membrane integrity returns.

13

Heart rate increases and cardiac output decreases because of

the initial fluid shifts and hypovolemia that occur after a burn injury.

14

Cardiac output may remain low until

18 to 36 hours after the burn injury.

15

Cardiac output increases with

fluid resuscitation and reaches normal levels before plasma volume is restored completely.

16

Curling’s ulcer,

an acute gastroduodenal ulcer that occurs with the stress of severe injury, may develop within 24 hours after a severe burn injury because of reduced GI blood flow and mucosal damage.