chronic CV pt 1 Flashcards
(41 cards)
exam findings for hyperlipidemia
skin lesions - eruptive or tendinous xanthomas
lipema retinalis
lipemic blood sample
dyslipidemia screening
all adults >20 years every 5 years
earlier and more often if familial hx
middle-older adults q1-2 years
when to start statin
LDL>100 + CV risk
maybe lower (LDL 55-70) for higher risk
low risk - >130 after lifestyle modification
women risk factor for CAD
PO contraception - d/c with dyslipidemia
statins AEs
myopathy/myosis, elevated LFTs, N/V/D, abd pain, HA, insomnia, rhabdo, hyperglycemia
statin monitoring
baseline LFTs
lipid panel at 6 week intervals
drug interactions
LFTs, CK if myalgias
consider decreasing dose when 2 consecutive LDL<40
statin contraindications
absolute - pregnancy, liver disease
relative - meds (cyclosporins, macrolides, antifungals, CYP 450 inhibitors)
ezetemibe indication, monitoring, CI
LDL reduction in statin-intolerant individuals or combo therapy
baseline LFTs
CI in hepatic impairment
bile acid sequesterants considerations & AE & CI
drug/drug interactions, vitamin malabsorption
may increase triglycerides, CI in TG>300
CONSTIPATION, dyspepsia, bloating, cramping, abd distention –>decrease adherence
CI in TG>300
hypertriglyceride treatment
TG>300
fibrates
niacin
fibrates AE, considerations, & CI
GI - abd bloating, N/V/D, gallstones
drug interactions ,monitor LFTs, monitor renal function
CI in renal & hepatic disease
niacin AE & monitoring & CI
flushing with itching
take ASA 30 mins before, take at night
monitor LFTs
CI - liver disease, severe gout
PCSK9 inhibitors
combo therapy w statin to lower LDL in those w family history
SQ injection
omega 3 fatty acid - icosapent ethyl
for marked hypertriglyceridemia
can increase LDL & prolong bleeding
serious risk in pregnancy
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CHD/CAD exam findings
S4
S3 - ventric dysfunction
obesity
leg edema
pulmonary congestion
diagonal ear crease
hair patterns
lab findings for CHD/CAD
ACS - troponin
lipid panel
elevated ESR/CRP
elevated homocystine
CHD/CAD diagnostics
coronary angiography - diagnostic
myocardial stress test - initially performed
EKG - normal
CHD/CAD managment
decrease risk!!!!
secondary - for secondary CAD with intermittent CP
antiplatelets, beta blockers - after MI or ACS, ACE/ARB
PCI revascularization
cardiomyopathy
cardiac muscle dysfunction that results in systolic or diastolic dysfunction that is not due to atherosclerosis, HTN, or valvular disease
dilated cardiomyopathy
-ventricular enlargement
-contractile dysfunction
-normal LV wall thickness
- systolic and diastolic dysfunction
most idiopathic
dilated cardiomyopathy s/s
s/s of gradual heart failure
heart failure exam findings
tachypnea
tachycardia
HTN
hypoxia
JVD
pulm edema
S3
murmur
hepatomegaly
peripheral edema
heart failure symptoms
fatigue
DOE
dyspnea
orthopnea
PND
increasing edema, weight gain, increasing abdominal girth