Chronic pain Flashcards

(52 cards)

1
Q

What is chronic pain

A

Pain >3 months persitsting beyond expected healing time for an episode of tissue damage
-> loss of function and impact on BPS model QOL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Causes of chronic pain

A

Nociceptice pain
Neuropathic pain
Nociplastic pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is nociceptive pain

A

Due to an organic disease
MSK eg osteoarthritis
Cancer pain, visceral pain etc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is neuropathic pain

A

Pathology eg peripheral neuropathy, MS, post herpetic pain etc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is nociplastic pain

A

Change/modulation - abnormal pain processing when no physical/organic damage has occurred to tissue or nerves

pain that arises from altered nociception despite no clear evidence of actual or threatened tissue damage causing the activation of peripheral nociceptors or evidence for disease or lesion of the somatosensory system causing the pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How is visceral pain often described

A

Aching, cramping, pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What makes somatic pain (skin, muscle, boens) distinguishable?

A

Aching, throbbing, sharp, stinging
Triggered by movement/plapation
Well lovalised - 1 finger point

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Central pain characteristics

A

CNS
Constant pain
Worsened by movements
Ass w paraesthesia or hypersenstivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does neuropathic pain feel like

A

Burning, coldness, tingling, electric-shocks.
Often hard to describe
Length dependent or dermatome distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Where are pain signals from the ascending pathway send to in the brain

A

Cortex - localises
Midbrain - general arousal
Limbic system - emotional
Periaqueductal gray or PAG - feeds into inhibitory pathwya

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Groups with higher incidence of chronic pain

A

Older age groups
Co-morbid disease: particularly depression and cardiovascular disease
Female gender
Socio-economic deprivation
Smokers
Alcohol dependence
Increased BMI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What modulates the descending pain pathwhya

A

PAG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What neurotransmitters foes PAG release to modulate pain response

A

GABA
Exogenous endorphins (which act on opioid receptors)
Serotonin
Noradrenaline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Causes of nociplastic chronic pain

A

Centreal sensitisation - increased responsiveness of nociceptors in CNS - non painful stimuli are painful
Reduced negative feedback - reduced inhibition in descending pathways - depression/anxiety/stress inhibit limbic and cortex
Somatisation - Psycholgical distress as physical pain or symtpoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Yellow flags - risk factors for developing chronic pain

A

Maladaptive health behavious
Adtoping passive vs active coping strategies
Anxiety, depression and social isolation
Lack of social support or over protective caregivers
Ongoing litigation related to original pain or injury source
Unresolved anger
Poor job satisfaction or extended sick leave

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Maladaptive health beliefs and behaviours examples that can make chronic pain worse

A

The belief that feeling pain means harm is occurring
Fear-avoidance of activities due to fear of pain/re-injury
Catastrophic thinking
Reliance on passive coping strategies (e.g. drugs and rest) rather than active (e.g. physiotherpay)
Low expectations of recovery
Adopting “the sick role”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Pain history questons

A

Current pain symptoms: SOCRATES
Impact of the pain: activities of daily living, social and psychological
Screen for red flags
Systems inquiry: associated conditions e.g. depression, IBS, connective tissue disease signs
Past medical history and other pain conditions
Drug history including opioid use and illicit drugs
Social history: support networks, job, finance
Ideas, concerns and expectations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Strategies for managing pain

A

Medication
Physiotherapy
Education and self care
Psychological

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What need to identify in chronic pain

A

Features which predispose, precipitate and perpetuate chronic pain
eg pain at nihgt -> poor sleep -> un-refreshing sleep and chronic tiredness -> increased pain

Identify cycles and manage them

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is the biggest risk factor for developing chronic pain

A

Acutely painful experience - post op pain, acute illness or traumatic accident
Poorly controlled or ass w psychological distress

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Positive diagnosis

A

Based on clinical findings, meet the criteria of blank
Rather than we have ruled out everything else so therefore it must be balnks = negtaive

22
Q

What is chronic primary pain vs crhonic pain

A

Chronic = persists over 3 months
Chronic priary pain = one or more anatomical regions characterised by significant emotional distress or funcitonal disability

23
Q

What conditions come under chronic primary pain

A

Chronic widespread ain
Complex regional pain syndrome
Chronic primary headache or orofacial pain
Chonic primary viscerla pain
Chronic primary MSK pain

24
Q

Methods for assessment of pain

A

Visual analogue
Faces pain scale
Verbal rating eg 1-10
McGill pain questionnaire - assess initial presentation

25
Psychological management of chronic pain
Explanation Reassurance Psychological therapies eg CBT, distraction techniques Mindfulness Exercise
26
Physical therapies for chronic pain management
RICE Acupuncture Massaeg Physiotherapy TENS machine
27
What treatments can be beneficial for chronic pain
CBT Graded exercise - beneficial for some
28
CBT how beneficial crhonic
How person thinks about, maanages pand lives w pain Reduce anxiety, worry and depression Reduces pain intensity, improve function and reduce negative appraisal and catastrophising
29
How does a TENS machine help chronic pain
Mechanical stimulation inhibits pain signalling Stimulates a-beta fibres (myelinated) which are quicker than C delta fibres - unyelinated - pain. Gets there first
30
Step 1 WHO pain ladder
Non opioids eg paracetemol, NSAIDs, +/- adjuvant
31
Step 2 WHO pain ladder
Codeine Dihydrocodeine Tramadol
32
Step 3 pain WHO ladder
Opioids for mod to sev Morpine Oxycodone Fentanyl
33
How does renal pain ladder differ from normal
Mild pain - NO NSAIDs step 2 - hydrocodone, oxycodone - both 5mg PO 4 hrs, , tramadol 15mg QDS 3 - hydromorphone -1mg PO Alfentanil - 100 micrograms
34
What neuropathic pain drug is esp recommended in diabetic neuropathy and post herpetic neuralgia
Gabapentin
35
What pain drug use in trigeminal neuralgia
Carbamaxepine
36
First line drug for neuropathic pain
Pregabalin
37
Which neuropathic pain drugs can prolong QTc interval
Amitryptilline Pregabalin
38
Options for use in soecialist pain clincis management
Local anaesthetic Ketamine Clonidine NSAIDs Topical capsacn TENS machine Facet joint injections for OA spine Spinal cord stimualators
39
what can opioids cause long term
Sedation Dizziness Nausea and vomiting Constipation Respiratory depression. Can also increase airway resistance and decrease the patency of the upper airways. Physical dependence and tolerance Delayed gastric emptying Opioid-induced Hyperalgesia Immune suppression Hormonal suppression Muscle rigidity Myoclonus poor self-related quality of life and employment status, increased healthcare use and worse pain (Faculty of Pain Medication).
40
What should all patients on long term opioids have
Regular laxatives Small supply of anti-emetics
41
Important Practice Points Regarding Opioids
if no useful pain relief from opioids within 2-4 weeks unlikely benefit long term. Short-term efficacy does not guarantee long-term efficacy There is no good evidence of dose-response with opioids, beyond doses used in clinical trials (up to 120mg morphine per day). There is no evidence for efficacy of high dose opioids in long term pain.
42
What need to prescribe for benefit of patient in chronic pain psych
duloxetine, fluoxetine, paroxetine, citalopram, sertraline or amitriptyline, If >16 and primary chronic pain improve pain, quality of life and psychological distress
43
Explanations for MUPS
Sensory sensitisation - CNS hyper reactive to normal stimuli eg peristalsis HPA axis dysfunciton - cortisol and immune linked. Somatisation - mental health disorders manifesting as physical symptoms
44
What is illness anxiety disorder
Cycle of recurrent anxiety around fears of ill health -> recurrent presentations health services despite reassurance Can be physical symptoms or MUPS
45
Features, cause and investigations for chronic mesenteric ischaemia
Pain worse after eating Acute episodes of bloody diarrhoea and pain Ass w vascular disease and signs CT/MR angiogram - reduced blood flow
46
Peptic ulcer disease as and features
Pain ass with eating, active bleed -> melaena Ass w NSAIDs, alcohol, H pylori
47
Fetaures of IBS
Pain relieved by defecation Change inn bowel habit, constipation, bloating
48
Chronic pancreatitis featires
Pain after eating Prev pancreatitis, alcohol, smoking Foul stools, weight loss CT scan - atrophic pancreas Lipase - raised or normal
49
Functional dyspepsia features
Fullness after eating and early satiety Eigastric pain and nausea and vomitting
50
What is centrally mediated abdominal pain syndrome
Pain principle feature Eating and defecation dont affect pain
51
What is an abdominal migraine and who does it occue in
Childhood Recurrent pain attacks Last up to 72 hours
52