Flashcards in CKD Deck (22):
What is the prevalence of CKD?
Is screening effective for CKD?
What are come risk factors for CKD?
What are some other risk factors for CKD?
->60 year old
-Treatment with nephrotoxic drugs
What is the definition of CKD?
Kidney damage or GFR <60 for greater than 3 months
What are the top 3 contributors to CKD?
What is the 1st stage of CKD?
Kidney damage with GFR >90
What is 2nd stage of CKD?
Kidney damage with GFR of 60-89
What is the 3rd stage of CKD?
Moderately decreased GFR at 30-59
What is the 4th stage of CKD?
Severely decreased GFR at 15-29
What is the 5th stage of CKD?
Kidney failure at GFR <15
What is the definition of kidney damage?
Pathological abnormality in blood or urine tests or imaging
- UA, Urine alb, pro/Cr and serum creatinine
What is the best measurement of GFR?
What is plasma creatinine good for?
What are the limitations of creatinine?
Inaccurate with mild renal impairment
- reduced in low muscle
- increase with high protein diet
- affected by certain drugs
What is Cystatin C?
-Low molecular wt produced by all nucleated cells
-Not affected by diet, gender, age, muscle mass
- affected by steroids
What is creatinine clearance good for?
Urine collections unreliable
- overestimates GFR
-Drug influences creatinine assays
What is the Cockroft-Gault formula?
-avoids urine collection
-Overestimates for obesity and low protein diet
- better than plasma creatinine for renal impairment
What is MDRD?
Modification of Diet in Renal Dz
- 186*Scr*age*0.742 (Females)* 1.210
What is CDK-EPI?
included age, sex, race and serum creatinine
What is the best approximation of true GRF?