Class 11 Deck 3

Question 1

What CV effects does hypothyroid patients have?

Answer 1

• Brady
• Decrease SV
• Decreased CO

Question 2

Armour thyroid combine what 2 things?

Answer 2

-T3 and T4 (T4:T3 = 4:1)

Question 3

What does armour thyroid treat?

Answer 3

• Hypothyroid (goiter)

- Regression of TSH tumors

Question 4

What is synthroid? what is the half life?

Answer 4

• T4 (deionated and converted to T3)

- 7 days

Question 5

What is liothyronine (cytomel)? and how does it compare to Synthroid?

Answer 5

• Levorotatory isomer of T3

- 2-3x more potent (rapid on off)

Question 6

Liothyronine (T3) (Cytomel®) has a higher incidence of what?

Answer 6

-Cardio side effects

Question 7

What does calcitonin do?

Answer 7

• released from thyroid gland

- Decreases plasma calcium

Question 8

When is calcitonin useful?

Answer 8

-treatment of pain and complications of Paget’s

Question 9

how do Propylthiouracil (PTU) and Methimazole (Tapazole®) work?

Answer 9

• Block synthesis of thyroid hormone
• Block T4 conversion to T3
• Only oral

Question 10

When are Propylthiouracil (PTU) and Methimazole (Tapazole®) useful?

Answer 10

-Hyperthyroid and Storm before thyroidectomy

Question 11

what are the side effects of Propylthiouracil (PTU) and Methimazole (Tapazole®)

Answer 11

-Granulocytopenia and agranulocytosis

Question 12

how do Thiocyanate and Perchlorate work?

Answer 12

-Block uptake of iodine by thyroid

Question 13

What is the oldest effective treatment for hyperthyroid? and how does it work?

Answer 13

• Iodide (Lugols solution)

- Inhibits release of thyroid hormone

Question 14

What is iodide combined with to treat hyperthyroidism before thyroidectomy?

Answer 14

-Propanolol

Question 15

How to treat thyroid storm?

Answer 15

• Cold crystalloids
• Sodium iodide
• Cortisol
• Propanolol
• Propylthiouracil
• Avoid ASA