Class 3 & 4 - Pharmacology Flashcards
(49 cards)
Bioavailability
how much drug is available to enter the cell
Chemical Name
description of the drug using the nomenclature of chemistry
Side Effect
a reaction to a drug that is known
Toxicity
degree of detrimental physiologic effects caused by excessive drug dosing
Indication
medical conditions for which the drug is given
Pharmacodynamics
what the drug does to the body
First Pass Effect
rapid hepatic inactivation of certain oral drugs; drug is completely inactivated
Absorption
movement of drug from its site of administration into the blood
Toxic Concentration
detrimental physiologic effects from excessive drug dose
Partial Agonist
mimic the action of endogenous regulatory molecules but at a lower level than agonists
Average Lethal Dose
dose that is lethal to 50% of the population
Drug Schedule
schedule 1, 2, 3, unscheduled
Generic Name
less complex than chemical names and is the name of the drug we most commonly use
Adverse Effect
undesired effect that occurs at normal drug doses
Hepatotoxicity
drugs that undergo metabolism and are converted to toxic products that can injure liver cells
Contraindication
conditions not to give the drug
Ions
molecules that have a net electrical charge that is either positive or negative
Polar Molecules
have an uneven distribution of charge but is overall neutral
Distribution
drug movement from the blood to the interstitial space and then to cells
Therapeutic Range
the range where the drug will have it effect
Average Effective Dose
ED50
Therapeutic Index
measure of a drugs safety; the higher the safer
OTC
over-the-counter
Trade Name
names under which the drug is marketed, e.g. Tylenol
