Class Notes - Cartilage and Bones Flashcards

1
Q

what is appositional growth

A

adjacent to perichondrium

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2
Q

what is interstitial growth

A

within the matrix of the cartilage

chondrocites divide -> move

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3
Q

what are the cells of the bone?

A

osteoprogenitor cells
osteoblasts
osteocytes
osteoclasts

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4
Q

what are osteoprogenitor cells

A
  • dividing stem cells
  • immature bone cells that will differentiate
  • youngest
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5
Q

what are osteoblasts

A

immature bone cells that create a matrix

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6
Q

what are osteocytes

A

mature cells, surrounded by lacuna

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7
Q

what are osteoclasts

A

derived from white blood cells, use hydrochloric acid

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8
Q

what is the extracellular matrix of the bone cells made up of

A

ground substance rich in minerals (hydroxyapatites -> mostly calcium and phosphate)
- collagen

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9
Q

what are the properties of bone tissues?

A
  • resistant to compression
  • resistant to tension
  • vascularized and innervated
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10
Q

why are bones organs?

A
  • contain all 4 types of connective tissue
  • also contain epithelial and nervous tissue
  • have numerous and diverse functions
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11
Q

how can you classify bones?

A

compact/spongy - tissue organization

long/short/flat/irregular - shape

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12
Q

diaphysis

A

elongated shaft of a long bone

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13
Q

epiphyses

A

the end of a long bone, attached to the shaft

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14
Q

metaphyses

A

(aka epiphyseal plates or epiphyseal lines)
plate of hyaline cartilage at the junction of the diaphysis (shaft) and epiphysis (end) of most bones in the growing skeleton; provides growth in the length of the bone

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15
Q

periosteum

A

membrane of fibrous connective tissue that covers the external surface of bones of the skeleton

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16
Q

endosteum

A

layer of cells lining the internal surfaces of bone, specifically, lining the central canals of osteons and the medullary cavity, and covering the trabeculae of spongy bone

17
Q

Marrow cavity

A
18
Q

what is the internal structure of flat bones

A

2 outer layers of compact bone

+ spongy bone middle

19
Q

how are osteocytes organized

A

osteocytes reside in lacunae

- osteocyte organized into osteons or haversian systems

20
Q

Haversian canal

A

tube-shaped unit of mature, compact bone; consists of concentric layers of bone lamellae surrounding a central canal

21
Q

Lamina

A

a thin layer or flat plate

22
Q

what are the steps of Intramembranous ossification?

A

Centers
Osteoid
Woven
Compact

23
Q

1st step of intramembranous ossification

A

(centers)

  • ossification centers develop in the fibrous connective tissue membrane
  • mesechymal cells cluster and differentiate into osteoblasts forming an ossification center
24
Q

2nd step of intramembranous ossification

A

osteoid)

  • osteoid is secreted and calcifies
  • osteoblasts continue to secrete osteoid, which calcifies in a few days
  • trapped osteoblasts become osteocytes