Classes of antibiotics

Question 1

B-Lactams

Answer 1

Inhibit enzymes involved in cross linking peptidoglycan
Cell Wall Synthesis Inhibitor

Bactericidal
Mainly Gram Positive

Question 2

Glycopeptides

+1

Answer 2

Targets proteins, preventing cross linking
Cell Wall Synthesis Inhibitor

Bactericidal
ONLY Gram Positive

Not absorbed by GI tract

Question 3

Purine Synthesis Inhibitors

Answer 3

Inhibit formation of purine bases (A&G)
Nucleic Acid Synthesis Inhibitor

Bacteriostatic

Question 4

Fluoroquinolones

Answer 4

Direct inhibition
Nucleic Acid Synthesis Inhibitor

Bactericidal
Mainly Gram Negative

Question 5

Aminoglycosides

Answer 5

Causes misreading of codon
Protein Synthesis Inhibitor

Bactericidal
Mainly Gram Negative

Question 6

Macrolides

+1

Answer 6

Prevent peptide bond forming
Protein Synthesis Inhibitor

Concentration dependant
Mainly Gram Positive

Effective for patients allergic to penicillin

Question 7

Tetracyclines

Answer 7

Block codon - No amino acid added to polypeptide chain
Protein Synthesis Inhibitor

Bacteriostatic
Mainly Gram Positive

Question 8

Oxazolidinones

Answer 8

Prevents subunits of ribosome joining
Protein Synthesis Inhibitor

Specific bacteria dependant
Mainly Gram Positive

Question 9

Cyclic Lipopeptides

Answer 9

Target membrane - Cause rapid depolarization
Protein Synthesis Inhibitor

Bactericidal
Mainly Gram Positive