Classes of Natural Products Flashcards
(13 cards)
What are the subclasses of alkaloids?
Phenylalkylamine: Epinephrine Colchicine Isoquinolone: Codeine Xanthine: Caffeine
What are the subclasses of terpenes?
Monterpenes : Menthol Diterpenes: Taxol (blocks depolemerization of microtubles) Sesquiterpenes/Triterpenes: Steroids
What are the subclasses of shikimic-acid?
Phenylpropenes: Spices like cinnamon, clove and myristicin Lignans: Etoposide (topoisomerase 2 inhibitors) Coumarins: Warfarin
What are glycosides derivatives of?
They are any of the other natural products classes that have a suger attached C-glycosides: sugar attached to the aglycone with C-C bond O-glycosides: Sigar attached to aglycone with O-C bond
Terpene (isoprene)
What are Polyketides derived from
Acetate derived becomes malonyl-CoA in the body
What are shikimic-acid derived from
From shikimic acid
What are the subclasses of polyketides?
Tetracyclines: Monocycline, doxycycline Macrolides: Clarithromycin, Azithromycin Statins
What are the alkaloids derived from?
General class of molecules that contain a basic nitrogen
Shikimic-Acid
Terpenes (geranyl pyrophosphate)
What are terpenes derived from?
From the building block of isoprene It becomes geranyl pyrophosphate in the body (which is 2 isoperenes together
Polyketides
