Classic Findings Flashcards
(103 cards)
1
Q
Anticentromere antibodies
A
Scleroderma
2
Q
Antidesmoglein antibodies
A
Pemphis vulgaris
3
Q
Anti-glomerular basement membrane antibodies
A
Goodpasture’s syndrome
4
Q
Antihistone bodies
A
Drug induced SLE
5
Q
Anti-IgG antibodie
A
Rheumatoid arthritis
6
Q
Antimitochondrial antibodies (AMA)
A
primary biliary cirrhosis
7
Q
Antineutrophil cytoplasmic antibodies (ANCAs)
A
Vasculitis
8
Q
Antiplatelet antibodies
A
Idopthathic thrombocytopenia purpura
9
Q
Anti-topoisomerase antibodies
A
Diffuse systemic scleroderma
10
Q
Anti-transglutaminase/anit-gliadin/anti-endomysial antibodies
A
Celiac disease
11
Q
Apple core lesion on abdominal x-ray
A
Colorectal cancer (L sided)
12
Q
Azurophilic peroxidase-positive granular inclusions in granulocytes adn myeloblasts
A
Auer rods (especially [M3] type)
13
Q
Bacitractin response
A
Sensitive: GAS Resistant: GBS
14
Q
Bamboo spine on x-ray
A
Ankylosing spondylitis
15
Q
Basophilic nuclear remnants in RBCs
A
Howell-Jolly bodies
16
Q
Basophilic stippling of RBCs
A
Lead poisoning or sideroblastic anemia
17
Q
Bloody tap on LP
A
subarachnoid hemorrhage
18
Q
Boot shaped heart on x-ray
A
Tetralogy of Fallot, RVH
19
Q
Branching gram-positive rods with sulfur granules
A
actinomyces israelii
20
Q
Bronchogenic apical lung tumor on imaging
A
Pancoast tumor
21
Q
Brown tumor of bone
A
Hyperparathyroidism or osteitis firosa cystica
22
Q
Cardiomegaly with apical arophy
A
Chagas disease
23
Q
Cellular cresecents in Bowman’s capsule
A
Rapidly progressive crescentic glomerulonephritis
24
Q
Chocolate cyst of ovary
A
Endometriosis
25
Circular grouping of dark tumor cells surrounding pale neurofibrils
Homer-Wright rosettes (neuroblastoma, meduloblastoma, retinoblastoma)
26
Colonies of mucoid Pseudomonas in lungs
Cystic fibrosis
27
Decreased alpha fetoprotein in amniotic fluid/maternal serum
Down syndrome or other chromosomal abnormality
28
Degneration of dorsal column nerves
Tabes dorsalis (tertiary syphilis), subacute cmobined degeneration
29
Depigmentation of neurons in substancia nigra
Parkinson's disease
30
Desquamated epithelium casts in sputum
Curshman's spirals
31
Disarrayed granulosa cells in eosinophilic fluid
Call-Exner bodies
32
Dysplastic squamous cervical cells with nuclear enlargement and hyperchromsia
Koilocytes (HPV)
33
Enlarged cells with intranuclear inclusion bodies
Owls eyes
34
Enlarged thyroid cells with ground glass nuceli
Orphan Annie's eyes nuclei (papillary carcinoma of thryoid)
35
Eosinophilic cytoplasmic inclusion in liver cell
Mallory bodies (Alcoholic liver disease)
36
Eosinophilic cytoplasmic inclusion in nerve cell
lewy body (PD)
37
Eosinophlic globule in liver
Councilman body (toxic or viral hepatitis)
38
Eosiniophilic inclusion bodies in cytoplasm of hippocampal nerve cells
Negri bodies of liver
39
Extracellular amyloid deposition in gray matter of brain
Senile plaques (AD)
40
Giant B cells with bilobed nuclei with prominent inclusions
Reed-Sternberg cells (Hodgkin's lymphoma)
41
Glomeruls-like structure surrounding vessel in germ cells
Schiller-Duval bodies (yolk sac tumor)
42
Hair on end appearence on x-ray
Beta-thalessemi, sickle cell anemia
43
hCG elevated
Choriocarcinoma, hydatidiform mole
44
Heart nodules
Aschoff bodies (rheumatic fever)
45
Heterphile antibodies
Infectious mononucleosis
46
Hexagonal, double pointed, needle-like crystals in bronchial secretions
Bronchial asthma
47
High level of d-dimers
DVT, pulomonary embolism, DIC
48
Hilar lymphadeonapthy, periperhal granulomatous lesion in middle or lower lung lobes (can calcify)
Ghon complex (primary TB)
49
Honeycomb lung on xray or CT
Interstitial pulomnary fibrosis
50
Hypercoagability
Trossusseau's syndrome (adenocarcinoma of pancreas or lung)
51
Hypersegemented neutrophils
Megaloblastic anemia
52
Hypertension, hypokalemia, metabolic alkalosis
Conn's syndrome
53
Hypochromic, microcytic anemia
Iron def. anemia, lead poisoning, thalassemia
54
Increased alpha-fetoprotein in amniot fluid/maernal serum
Dating error, anecephaly, spina bifida (neural tube defects)
55
Increased uric acid levels
Gout, Lesch-nyan syndrome, tumor lysis syndrome, loop and thiazide diuretics
56
Intranuclear eosinophilic droplet like bodies
Cowdry type A bodies (HSV or CMV)
57
Iron containing nodules in alveolar septum
Ferriginous bodies (asbestosis --> increased meshothelioma)
58
Keratin pearls on a skin biopsy
Squamous cell carcinoma
59
Large lysosomal vesicles in phagocytes, immunodeficiency
Chediak-Higashi disease
60
Lead pipe appearence of colon on barium enema xray
Ulcerative colitis (loss of haustra)
61
Linear appearence of IgG depoistion on glomerular basement membrane
Goodpasture's syndrome
62
Low serum ceruloplasmin
Wilson's disease
63
Lumpy bumpy appearnce of gomerule on immunoflourescence
Poststreptoccol glomerulonephritis (iimune complex deposition of IgG and C3b)
64
Lytic bone lesions on xray
Multiple myeloma
65
Mammary gland cyst
Fibrocystic change of the breast
66
Monoclonal antibody spike
Multiple myeloma: Monoclonal gammopathy of undetermined signifigiance, Waldenstorms macroglobulinemia, Primary amyloidosis
67
Mucin filled cell with peripheral nucleus
Signet ring (gastric carcinoma)
68
Narrowing of bowel lumen on barium xray
String sign (Crohn's disease)
69
Necrotizing vasculitis and necrotizing glomerulonephriti
Granulomatosis with polyangiitis adn Goodpasture's syndrome
70
Needle shaped negative birefringent crystals
Gout (monosodium urate crystals)
71
Nodular hyaline deposits in glomeruli
Kimmelstiel-Wilson nodules (diabetic nephropathy)
72
Novobiocin response
Sensitive: S. epidermidis Resistant : S saprophyticus
73
Nutmeg appearence of liver
Chronic passive congestion of liver due to right heart failure
74
Onion skin periosteal reaction
Ewing's sarcoma
75
Optochin respomse
Sensitive: S. pneumoniae, Resistnace : Viridans streptococcus
76
Periosteum raised from bone, creating triangular area
Codman's triangle on xray (osteosarcoma, Ewing's sarcoma, pyogeni osteomyelitis)
77
Podocyte effacement on electron micropscopy
Minimal change disease
78
Polished ivory like appearence on bone cartilage
Eburnation
79
Pasammoma bodies
Menagiomas, papillary thryoid carcinoma, mesothelioma, papilarry serous carcinoma fo the endometrium and ovary
80
Pseudopalisading tumor cells on brain biopsy
Gliobalsota multiforme
81
RBC casts in urine
Acute glomerulonephritis
82
Rectangular crystal like, cytoplasmic inclusions in Leydig cells
Reinke crystals (Leydig cell tumor)
83
Renal epithelial casts in urine
Acute toxic/viral nephrosis
84
Rhomboid crystals, positively bifringement
Pseudogout (calcium pyrophosphate dihydrate crystals)
85
Rib notching
coartaction of the aorta
86
Ring-enhancing brain lesion in AIDs
toxoplasma gondii, CNS lymphoma
87
Sheets of medium sized lymphoid cells with scattered pale tingible body-laden macrophages (starry sky)
Burkitt's lymphoma (t[8,14], c-myc activation)
88
Silver staining spherical aggregation of tau proteins in neurons
Pick bodies
89
Soap bubble in femur or tibia on xray
Giant cell tumor of bone
90
Spikes on basement membrane, dome-like subepithelial deposits
Membranous glomerulonephritis (may progress to nephrotic syndrome)
91
Stacks of RBCs
Roleaus formation (high ESR, MM)
92
Stipppled vaginal epithelial cells
Clue cells (gardnerella vaginalis)
93
Tennis racket shaped cytoplasmi organelles in Langerharn cells
Birbeck granules (Langerhans cell histiocytosis or histocytosis X)
94
Thrombi mage of red/white layers
Lines of Zane (arterial thrombus, layers of platlets/RBCs)
95
Thumb sign on lateral xray
Epiglottitis (Baemophilus influenzae)
96
Thyroid like appearence of kidney
Chronic bacterial glomerulonephritis
97
Tram-track appearence of capillary loops of glomerular basement membrane on light microscopy
membranoproliferative glomerulopnephritis
98
Triglyceride accumulation in liver cell vacuoles
Fatty liver disease (alcholic or metabolic)
99
Waxy casts with very low yrin flow
Chronic end stage renal disease
100
WBC casts in urine
Acute pyelonephritis
101
WBCs that look smudged
CLL (almost always B)
102
Wire loop glomerular capillary appearnece on light microscopy
Lupu nephropathy
103
Welloish CSF
Xanthochromia (due to subarachnoid hemorrhage)
