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Classic/Relevant Treatments Flashcards

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1
Q

Absence seizures

A

Ethosuxamide

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2
Q

Acute gout attack

A

NSAIDs, colchicine, glucocorticoids (NOT allopurinol)

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3
Q

Acute promyelocytic leukemia (M3)

A

All-trans retinoic acid

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4
Q

ADHD

A

Methylphenidate, CBT, atomoxetine

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5
Q

Alcoholism

A

Disulfiram, acamprosate, naltrexone, supportive care

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6
Q

ETOH withdrawal

A

Benzos

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7
Q

Anorexia

A

Nutrition, psychotherapy, mirtazepine

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8
Q

Anticoagulation during pregnancy

A

Heparin (higher water solubility)

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9
Q

Arrhythmia in damaged cardiac tissue

A

Class IB anti-arrhythmic (lidocaine, mexiletine)

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10
Q

B12 deficiency

A

Vitamin B12 supplementation (work-up cause wiwth Schilling test)

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11
Q

BPH

A

alpha-1 antagonists, 5-alpha reductase inhibitors, PDE-5 inhibitors

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12
Q

Bipolar disorder

A

Mood stabilizers (lithium, VPA, carbamazepine), atypical antipsychotics

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13
Q

Breast cancer in post menopausal women

A

Aromatase inhibitors (anastrozole)

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14
Q

Buerger disease

A

Smoking cessation

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15
Q

Bulimia nervosa

A

SSRIs

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16
Q

Candida albicans

A

Topical azoles (vaginitis); nystatin, fluconazole, caspofungin (oral/esophageal); fluconazole, caspofungin, amphotericin B (systemic)

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17
Q

Carcinoid syndrome

A

Octreotide

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18
Q

Chlamydia trachomatis

A

Doxycyclin/azithromycin (+ ceftriazone for gonorrhea coinfection), erythromycin eye drops (PPx for infants)

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19
Q

Chronic gout

A

XO inhibitors (e.g. allopurinol, febuxostat)

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20
Q

Chronic hepatitis B/C

A

IFN-alpha (HBV and HCV); ribavirin, simeprevir, sofosbuvir (HCV)

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21
Q

CML

A

Imatinib

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22
Q

Clostridium botulinum

A

Antitoxin

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23
Q

C. difficile

A

Oral metronidazole; if refractor, oral vancomycin

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24
Q

C. tetani

A

Antitoxin

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25
CMV
Ganicyclovir, foscarnet, cidofovir
26
Crohn disease
Corticosteroids, infliximab, azathioprine
27
Cryptococus neoformans
Fluconazole (in AIDS patients)
28
Cyclophosphamide-induced hemorrhagic cystitis
Mesna
29
Depression
SSRIs (first-line), SNRIs, atypicals, TCAs, MAOIs
30
Diabetes insipidus
Desmopression (central); HCTZ, indomethacin, amiloride (nephrogenic)
31
DM type 1
Dietary intervention (low carbohydrate) + insulin replacement
32
DM type 2
Dietary intervention, oral hypoglycemics, and insulin (if refractory)
33
DKA
Fluis, insulin, K+
34
Enterococci
Vancomycin, aminopenicillins, cephalosporins
35
Erectile dysfunction
SIldenafil, taldalafil, vardenafil
36
ER+ breast cancer
Tamoxifen
37
Ethylene glycol/methanol intoxication
Fomepizole (alcohol dehydrogenase inhibitor)
38
Haemophilus influenzae (B)
Rifampin (prophylazis)
39
Generalized anxiety disorder
SSRIs, SNRIs (first-line), buspirone (second line)
40
Granulomatosis wiht polyangiitis (Wegener)
Cyclophosphamide, corticosteroids
41
Heparin reversal
Protamine sulfate
42
HER2/neu+ breast cancer
Herceptin (Trastuzumab)
43
Hyperaldosterone
Spironolactone
44
Hypercholesterolemia
Statins (first-line)
45
Hypertriglyceridemia
Fibrate
46
Immediate anticoagulation
Heparin
47
Infertility
Leuprolide, GnRH (pulsatile), clomiphene
48
Influenza
Oseltamivir, zanamivir
49
Kawasaki disease
IVIG, high-dose ASA
50
LEgionella pneumophila
Macrolides (e.g. azithromycin)
51
Long-term anticoagulation
Warfarin, dabigatran (thrombin inhibitor), rivaroxaban (Xa inhibitor), apixaban (Xa inhibitor)
52
Malaria
Chloroquine, mefloquine, atovaquone/proguanil (for blood schizont), primaquine (for liver hypnozoite)
53
Malignant hyperthermia
Dantrolene
54
Medical abortion
Mifepristone
55
Migraine
Abortive therapies (e.g. sumitriptan, NSAIDs); prophylaxis (e.g. propranolol, topiramate, CCBs, amitryptaline)
56
Multiple sclerosis
Disease-modifying therapies (e.g. beta-IFN, natalizumab); for acute flares, use IV steroids
57
Mycobacterium tuberculosis
RIPE (rifampin, isoniazid, pyrazinamide, ethambutol)
58
Neisseria gonorrhoeae
Ceftriazone (add doxycycline to cover likely concurrent C. trachomatis)
59
Neisseria meningitidis
PCN/ceftriaxone, rifampin (PPx)
60
Neural tube defect prevention
Prenatal folic acid
61
Osteomalacia/rickets
Vitamin D supplementation
62
Osteoporosis
Calcium/vitamin D supplementation (PPx); bisphosphonates, PTH analogues, SERMs, calcitonin, denosumab (treatment)
63
Patent ductus arteriosus
Close with indomethacin, open/maintain with PGE analogues
64
Pheochromocytoma
Alpha antagonists (e.g. phenoxybenzamine)
65
PCP
TMP-SMX (PPx in AIDS patients)
66
Prolactinoma
Cabergoline/bromocriptine (DA agonists)
67
Prostate adenocarcinoma/uterine fibroids
Leuprolide, GnRH (continuous)
68
Prostate adenocarcinoma
Flutamide
69
Pseudomonas aeruginosa
Antipseudomonal PCNs, aminoglycosides, carbapenems
70
Pulmonary arterial hypertension (idiopathic
Sildenafil, bosentan, epoprostenol
71
Rickettsia rickettsii
Doxycycline, chloramphenicol
72
Schizophrenia (negative symptoms)
Atypical antipsychotics
73
Schizophrenia (positive symptoms)
Typical and atypical antipsychotics
74
SIADH
Fluid restriction, IV hypertonic saline, conivaptan/tolvaptan, demeclocycline
75
Sickle cell disease
Hydroxyurea (increases HgbF)
76
Sporothrix schenckii
Itraconazole, oral potassium iodide
77
Stable angina
Sublingual nitrogen
78
Staphlococcus aureus
MSSA: nafcillin, oxacillin, dicloxacillin (antistaphlococcal PCNs); MRSA: vancomycin, daptomycin, linezoline, ceftaroline
79
Streptococcus bovis
PCN ppx, evaluation for colon cancer if linked to endocarditis
80
Streptococcus pneumoniae
PCN/cephalosporin (systemic infection, pneumonia), vancomycin (meningitis)
81
Streptococcus pyogenes
PCN ppx
82
Temporal arteritis
High dose steroids
83
Tonic-clonic seizures
Levetiracetam, phenytoin, VPA, carbamazepine
84
Toxoplasma gondii
Sulfadiazine + pyrimethamine
85
Treponema pallidum
PCN G
86
Trichomonas vaginalis
Metronidazole (Pt and partner)
87
Trigeminal neuralgia (tic douloureux)
Carbamazepine
88
Ulcerative colitis
5-ASA preparations (e.g. mesalamine), 6-mercaptopurine, infliximab, colectomy
89
UTI ppx
TMP-SMX
90
Warfarin reversal
FFP (acute), vitamin K (chronic)
91
Prevention of post-surgical infection
Cefazolin (ancef)

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