CLASSIFICATION OF VIRUSES(Dr. Oshun)

Question 1

Parvoviridae:
Linear/circular
Single/Double Stranded
kb/kbp in size
Example

Answer 1

Linear, single-stranded DNA
5.6kb
Human Parvovirus B19

Question 2

Polyomaviruses:
Linear/circular
Single/Double Stranded
kb/kbp in size
Example

Answer 2

Circular, double-stranded DNA
5kbp
JC Virus, BK virus

Question 3

Papillomaviridae:
Linear/circular
Single/Double Stranded
kb/kbp in size
Example

Answer 3

Circular, double-stranded
8kbp in size
Human papillomavirus( over 100 genotypes)

Question 4

Hepdnaviruses:
Linear/circular
Single/Double Stranded
kb/kbp in size
Example

Answer 4

Circular, double-stranded DNA
3.2 kbp in size
Hepatitis B virus

Question 5

Herpesviridae:
Linear/circular
Single/Double Stranded
kb/kbp in size
Example

Answer 5

Linear, double-stranded DNA
125-240kbp in size
Varicella-Zoster virus, Human Cytomegalovirus

Question 6

Poxviridae:
Linear/circular
Single/Double Stranded
kb/kbp in size
Example

Answer 6

Linear, double-stranded DNA
130-375kbp in size
Small pox

Question 7

Adenoviridae:
Linear/circular
Single/Double Stranded
kb/kbp in size
Example

Answer 7

Linear, double-stranded DNA
26-54kbp in size
Human Adenoviruses(51 types)

Question 8

Concerning the species, EBOLAVIRUS ZAIRE, classify it into:
Order:
Family:
Genus:
Species:

Answer 8

Order: Mononegavirales
Family: Filoviridae
Genus: Ebolavirus
Species: Ebolavirus zaire

Question 9

Concerning HERPES SIMPLEX VIRUS TYPE 1, classify it into:
Order:
Family:
Subfamily:
Genus:
Species:

Answer 9

Order: Herpesvirale
Family: Herpesviridae
Subfamily: Alphaherpesvirinae
Genus: Simplexvirus
Species: Herpes Simplex virus type 1

Question 10

Examples of genus in family Parvoviridae:

Mnemonic: PED

Answer 10

Parvovirus
Erythrovirus(Erythroparvovirus)
Dependovirus

Question 11

Examples of genus in family Poxviridae:

Answer 11

Orthopox,
Suispox(swinepox)
Avipox(avianpox)
Mollusci pox(molluscum contagious)

Question 12

Examples of genus in family Arenaviridae:

Answer 12

Lassa
Mopeia (Mozambique)
Junin (Argnetina)
Machupo(Bolivia)
Lymphocytic Choriomeningitis

Question 13

Examples of genus in family Adenoviridae:

Answer 13

Mastadenovirus eg Human Adenovirus(several serotypes)

Question 14

Examples of genus in family Hepadnaviridae:

Answer 14

Hepadnavirus eg Hepatitis B virus

Question 15

Examples of genus in family Herpesviridae:

Answer 15

Simplex virus, Varicello virus, Cytomegalovirus, Roseolovirus, Lymphocryptovirus

Question 16

Examples of genus in family Astroviridae:

Answer 16

Astrovirus

Question 17

Examples of genus in family Bunyaviridae:

Answer 17

Bunyavirus, Nairovirus/Orthonairovirus, Hantavirus/Orthohantavirus, Phlebovirus

Question 18

Examples of genus in family Caliciviridae:

Answer 18

Norwalk, Hepatitis E virus

Question 19

Examples of genus in family Coronaviridae:

Answer 19

Coronavirus,SARS virus

Question 20

Examples of genus in family Filoviridae:

Answer 20

Ebola, Marburg

Question 21

Examples of genus in family Flaviviridae:

Answer 21

Yellow fever virus, dengue virus, West nile river virus, Hepatitis C virus

Question 22

Examples of genus in family Orthomyxovirus :

Answer 22

Influenza A, B, C

A- from humans, mammals and birds
B&C- not associated with humans

Question 23

Examples of genus in family Paramyxoviridae:

Answer 23

Parainfluenza, Human metapneumovirus, Mumps

Question 24

Examples of genus in family Picornaviridae:

Mnemonic: HER

Answer 24

Enterovirus, Hepatovirus, Rhinovirus

Question 25

Examples of genus in family Reoviridae:

Answer 25

Rotavirus

Question 26

Examples of genus in family Retroviridae:

Answer 26

Lentivirus spp-HIV HTLV(Human T-cell Leukemia virus)

Question 27

Examples of genus in family Rhabdoviridae:

Answer 27

Rabies virus, Lyssavirus Vesiculovirus

Question 28

Examples of genus in family Togaviridae:

Answer 28

Alphavirus (Chikungunya), Rubivirus(Rubella virus)

Question 29

Concerning Picornaviridae - small (_______), _____ -resistant viruses exhibiting _____ symmetry. –The RNA genome is _____ stranded and ____ sense (ie, it can serve as an ______) and is _____ in size. –Enteroviruses including _____ –Rhinoviruses

Answer 29

•28–30 nm Ether Cubic •single Positive mRNA 7.2–8.4 kb • Poliovirus

Question 30

Orthomyxoviridae - ______, enveloped viruses exhibiting _____ symmetry. Particles are either _______ or _______, with surface projections that contain _______ or _______ activity. The genome is ______, ______, ______ -sense, ______-stranded RNA, totaling ____ in size. Example: – _________

Answer 30

• 80- to 120-nm,helical •round, filamentous, hemagglutinin or neuraminidase • linear, segmented, negative , single, 10-13.6kb • Example: Influenza Virus

Question 31

• Paramyxoviridae - ______ , _____ -stranded, ________ , ______ -sense RNA is ____ in size. • Examples:

Answer 31

• Linear, single, nonsegmented, negative, 16–20 kb •mumps, measles, parainfluenza, metapneumo, and respiratory syncytial viruses.

Question 32

Filoviridae- ______, ______ viruses that may appear very long and _____. • They typically are ______ wide and about ______ long. The envelope contains large _____ . –The genome is ______ , _____ -sense, _____ -stranded. –RNA, _____ in sizegenus: Filovirus e.g _____, _____

Answer 32

• enveloped, pleomorphic, threadlike • 80 nm wide and about 1000 nm long • peplomers •linear,negative, single • 19kb • Ebola, Marburg

Question 33

Retroviridae : _____, ______ viruses (_______in diameter) whose genome contains ____ copies of _____ , _____- sense, ______- stranded RNA of the same polarity as _____. Each monomer RNA is ___kb in size. • Particles contain a ______ nucleocapsid within a _______ capsid. • Replication is unique; the virion contains a ___________ that produces a DNA copy of the ___ genome •Examples(2):

Answer 33

• spherical, enveloped, (80-110nm) • Two, linear, positive, single, viral mRNA • 7-11kb •helical, icosahedral • reverse transcriptase enzyme, RNA • HIV, HTLV