Clin Lab - Endocrine Diagnostics Overview Flashcards
Draw the Endocrine system subdivisions
DONE
What can go wrong?
three major categories
- Production issues by gland
- Regulation issues
- Hormone from another sourse
Production issues by gland examples.
- overproduction of hormone
- underproduction of hormone
- inappropriate release of hormone
Hormone from another source examples.
- endogenous source
- (exogenous source)
Regulation issues examples.
- loss of responsiveness to hormone
- loss of negative feedback
Easiest ways to measure endocrine function
- target organ output
- endocrine gland hormone e
- pituitary gland hormone
Hard way to measure endocrine function
hypothalamus factors
Hypofunction
Disorder: Primary (gland issue)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:
Endocrine gland hormone level: decr
Pituitary gland SH level: incr
Define hypofunction
decreased target organ output
Hypofunction
Disorder: 2ndary (pituitary issue)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:
Endocrine gland hormone level: decr
Pituitary gland SH level: decr
Hypofunction
Disorder: Tertiary (hypothalamus issue - rare)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:
Endocrine gland hormone level: decr
Pituitary gland SH level: decr
Hypofunction
Disorder: Target organ issue (rare)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:
Endocrine gland hormone level: incr
Pituitary gland SH level: incr
Define Hyperfunction
increased target organ action
Hyperfunction
Disorder: Primary (gland issue)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:
Endocrine gland hormone level: incr
Pituitary gland SH level: decr
Hyperfunction
Disorder: 2ndary (pituitary issue)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:
Endocrine gland hormone level: incr
Pituitary gland SH level: incr
Hyperfunction
Disorder: Tertiary (hypothalamus issue - rare)
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:
Endocrine gland hormone level: incr
Pituitary gland stimulating hormone level: incr
Hyperfunction
Disorder: Exogenous source - endocrine hormone mimic
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:
Endocrine gland hormone level: decr
Pituitary gland stimulating hormone level: decr
Hyperfunction
Disorder: Exogenous source - pituitary stimulating hormone mimic
Endocrine gland hormone level:
Pituitary gland stimulating hormone (SH) level:
Endocrine gland hormone level: incr
Pituitary gland stimulating hormone level: decr
List endocrine organs
- hypothalamus
- pituitary gland
- thyroid
- parathyroid
- adrenal glands
- pancreas
- ovaries/testes
List endocrine related organs & their homrone
- skin (calcitriol)
- heart (BNP)
- stomach (gastrin, somatostatin, leptin)
Describe a primary disorder
the endocrine organ itself is affected
Describe a secondary disorder
the pituitary gland is affected & releasing too much/too little of the hormone(s) that influences the endocrine organ
Describe a tertiary disorder
the hypothalamus is affected & releasing too much/too little of the releasing factor(s) that influence the pituitary (rare!)
Function of the anterior pituitary
releases prolactin & growth hormone that act on target tissues, not another endocrine gland