Clin Phys Week 1 E Flashcards Preview

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Flashcards in Clin Phys Week 1 E Deck (21):
1

What does epimysium cover?

Entire muscles

2

What does perimysium cover?

Fascicles (bundles of muscle fibres)

3

What does endomysium cover?

Muscle fibres (cells)

4

What are the micro structures of muscles?

Myofibres (Muscle cells)

Intracellular proteins (myofilaments)

Myofibrils (made of long lengths of sacromeres)

Sacromeres (smallest functional unit of a muscle)

5

What are the universal characteristics of muscle tissue?

Responsiveness

Conductivity

Contractility

Extensibility

Elasticity

6

What is responsiveness?

The capability of the muscle to respond to chemical signals, stretch or other signals and responding with electrical changes across the membrane

7

What is conductivity?

Local electrical charge triggers a wave of excitation that travels along the muscle fibre

8

What is contractility?

The muscle fibre is shortened when stimulated

9

What is extensibility?

The muscle fibre is capable of being stretched

10

What is elasticity?

The muscle fibre returns to its original resting length after being stretched

11

What is the sarcolemma and what are it's features?

The muscle cell membrane (similar to plasma membrane of normal cells)

It forms a layer over the outside of the cell on the exterior surface of the muscle. It has transverse tubules (t-tubules) extending deep into the muscle cell in order to be in contact with all myofibrils of the muscle. It does this so that it can effectively activate all muscle fibres as it is used to propagate the action potential.

12

What is the sarcoplasm?

The muscle cell cytoplasm. It is filled with myofilaments organised into sacromeres/ myofibrils.

13

What is the sarcoplasmic reticulum? What are it's features?

The equivalent of the smooth endoplasmic reticulum for muscle cells.It comprises of 2 parts:

tubules: hollow pipes which run perpendicular to t-tubules of the sarcolemma

terminal cisternae: large end chambers of the sarcoplasmic reticulum that join the t-tubules.

 

The sarcoplasmic reticulum contains calcium, which is essential for skeletal muscle contraction. One t-tubule and 2 terminal cisternae form one triad.

14

What are the myofilaments?

There are 2 types of myofilaments:

Contractile filaments:-actin-myosin.

Regulatory proteins:-troponin-tropomyosin

15

What is a sarcomere?

It is the functional contractile unit of the muscle. One myofibrils is made of a chain of many sarcomeres.It is a specific arrangement of contractile and regulatory proteins.

16

What would you see in the I-Band?

It is the area between the z-disc and the myosin fibres in which you would only see actin filaments.

17

What would you see in the H-Zone?

This is the area between the M-line and the actin filaments in which you would only see myosin filaments

18

What is the M-Line?

The area in the middle of the sarcomeres in which you would see myosin filaments joined together by accessory proteins to hold them in place.

19

What is the A-Band?

The area of the sarcomeres where the actin and myosin filaments overlap.

20

What is titin?

An elastic protein that connects the myosin filaments to the z-disc

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