Flashcards in Clinical GFR and Patterns Of Clearance Deck (11):
Ideal substances to calculate GFR?
Clinical substance used to calculate GFR?
Creatinine filtration/excretion mechanics?
1. Almost all freely filtered by kidney
2. A small portion is secreted
Glucose mechanics in the kidney?
1. Glucose is always reabsorbed until it hits TM (⬆️Glucose concentration)
Why is creatinine Clearance > than inulin?
Because some creatinine is always secreted.
Inulin is not secreted nor reabsorbed
Normal urine osmolality?
1. 300 mOsm/Kg
What does an increase H2O Clearance produce in terms of urine and plasma osmolality?
1. ⬇️ Urine osmolality
2. ⬆️ Plasma osmolality
What does an decrease in H2O Clearance produce in terms of urine and plasma osmolality?
1. ⬆️Urine osmolality
2. ⬇️Plasma osmolality
Similarities between Sodium and Urea in Kidney mechanics ?
1. Both are excreted and some of it is reabsorbed
Aldosterone and ANP effects on FeNa? (Fractional extraction of sodium)
1. Aldosterone: ⬇️FeNa+ (⬆️reabsorption)
2. ANP: ⬆️FeNa+ (⬇️reabsorption)