Clinical GFR and Patterns Of Clearance Flashcards Preview

Renal Physiology > Clinical GFR and Patterns Of Clearance > Flashcards

Flashcards in Clinical GFR and Patterns Of Clearance Deck (11):
1

Ideal substances to calculate GFR?

1. Inulin
2. Mannitol
3. Sucrose

2

Clinical substance used to calculate GFR?

1. Creatinine

3

Creatinine filtration/excretion mechanics?

1. Almost all freely filtered by kidney
2. A small portion is secreted

4

Glucose mechanics in the kidney?

1. Glucose is always reabsorbed until it hits TM (⬆️Glucose concentration)

5

Why is creatinine Clearance > than inulin?

Because some creatinine is always secreted.

Inulin is not secreted nor reabsorbed

6

Normal urine osmolality?

1. 300 mOsm/Kg

7

What does an increase H2O Clearance produce in terms of urine and plasma osmolality?

1. ⬇️ Urine osmolality
2. ⬆️ Plasma osmolality

8

What does an decrease in H2O Clearance produce in terms of urine and plasma osmolality?

1. ⬆️Urine osmolality
2. ⬇️Plasma osmolality

9

Similarities between Sodium and Urea in Kidney mechanics ?

1. Both are excreted and some of it is reabsorbed

10

Aldosterone and ANP effects on FeNa? (Fractional extraction of sodium)

1. Aldosterone: ⬇️FeNa+ (⬆️reabsorption)
2. ANP: ⬆️FeNa+ (⬇️reabsorption)

11

Why does an elevated ADH ⬆️ plasma urea?

⬆️ Urea reabsorption