Clinical signifcance

Question 1

Name a clinical condition related to epithelial tissue

Answer 1

. Pemphigus

Question 2

What is pemphigus?

Answer 2

• Disorder of junctional complexes
  . Autoimmune disease : antibodies are produced against desmosome specific cadherins (desmogleins) in the skin so the junctions break
  . Causes blistering & affects keratinocytes & mucous membranes