Clinical thyroid disease - hyperthyroidism Flashcards
What condition shows a raised T3,T4 and low TSH
Hyperthyroidism
What condition shows a raised TSH and low T3 and T4
Hypothyroidism
What condition shows a low TSH and a normal T3 and T4
subclinical hyper thyroidism
What condition causes raised TSH and normal T3 and T4
Subclinical hypothyroidism
How is thyroid hormone secretion regulated
If there is excess thyroid hormone being produced, negative feedback occurs with the T3 and T4 on the hypothalamus so less TRH from the hypothalamus and TSH from the anterior pituitary are released
What is another name for hyperthyroidism
Thyrotoxicosis
What is the most common cause of hyperthyroidism
Grave’s disease
What are the primary causes of hyperthyroidism
Grave’s disease
Toxic multi nodular goitre
Toxic adenoma
What are the secondary causes of hyperthyroidism
Pituitary adenoma secreting excess TSH
Which gender does Grave’s disease more commonly occur in
female
What is needed to diagnose Grave’s disease
Hyperthyroidism and thyroid antibodies (TSH receptor antibodies)
Who does subacute (de Quervain’s) thyroiditis most commonly affect
Younger patients less than 50
What causes subacute (de Quervain’s) thyroiditis
Viral trigger - enteroviruses
How is subacute thyroiditis treated
short term steroids and NSAIDs
How does subacute thyroiditis present
Painful goitre
fever
myalgia
increased ESR
