CLL Flashcards
(6 cards)
1
Q
CLL Presentation
A
Infections, anaemia, bruising
Weight loss, night sweats, fatigue
2
Q
CLL Risk factors
A
FmHx of cancer, pesticides/chemicals
3
Q
CLL Investigations
A
FBC: lymphocytosis, anaemia, thyombocytopenia, uric acid
Blood smear
Bone marrow biopsy: flow cytometry
CT for staging
Direct coombs test (AIHA)
4
Q
CLL Treatment
A
Watch and wait for stage 0-2
RCF for young/healthy patients:
Rituximab, cyclophosphamide, fludarabine
Transfusions, infections management, allogenic bone marrow transplant, allopurinol / pred
5
Q
CLL Complications
A
SE of treatment: ulcers, bowel habit, appetite, TLS
Haemolytic anaemia, ITP
Neutropenic sepsis
6
Q
CLL Progress / Review
A
Haematologist: bloods every 6 - 12 months
