Clostridia Flashcards Preview

Clin Med 1 Test 3 > Clostridia > Flashcards

Flashcards in Clostridia Deck (19):
1

what is the classification of Clostridial species

GP spore-forming rod, anaerobes

2

where are Clostridial spp's found (3)

soil, aquatic sediment, GI of animals

3

the 4 Clostridial spp's of CONCERN

perfringens, difficile, tetani, botulinum

4

in what illnesses is C. perfringens the culprit (3)

food poisoning, surgical inf, gas gangrene

5

what is Clostridial Myonecrosis

gas gangrene

6

MC predis[osing condition to C. Perfringens inf

injection drug use

7

how does gas gangrene appear (3 features)

pale to colorful skin, swelling with possible subQ emphysema, brown malodorous discharge

8

3 necessary steps to gas gangrene tx

surgical debridement, PCN q3hrs IV, HBO2

9

what is deadly about C tetani

it produces neurotoxin tetanospasmin leading to airway obstruction

10

how long after infection before signs of tetanus appear

5days to 15 WEEKS (avg ~10 days)

11

name of rigidity in mm's of back, neck, ABD

Opisthotonis

12

Ddx for tetanus (3)

meningitis, tranquilizer use (phenothiazine, thorazine), rat poisoning (strychnine, compazine)

13

3 necessary steps to tetanus tx

sedation, ventalation, human tetanus globulin (TIG) administration

14

MCC botulism

home-canned foods (smoked meats, vac-packed fish)

15

why do infants get botulism

sensitive to the small amt of C. botulinum in honey

16

what is the caue of wound assoc botulism

drug injection

17

what is the course of the dz of botulism

diplopia, ptosis, CN palsies, paralysis (resp failure)

18

Ddx for botulism (3)

myasthenia gravis, Gillian Barre Syndrome (C Miller Fisher variant), Vertebrobasilar insufficiency

19

3 necessary steps to botulism tx

get antitoxin from CDC, ventilate, IV fluids