CM Flashcards

(48 cards)

1
Q
  1. Total renal BLOOD flow
  2. Total renal PLASMA flow
A
  1. 1,200 ml/min
  2. 600-700 ml/min
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2
Q

renal threshold for glucose

A

160-180 mg/dl

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3
Q
  1. Regulates water reabsorption in dct and cd
  2. Dse under dis hormone
A
  1. ADH/Vasopressin
  2. DI (adh deficiency), SIADH (adh excess)

Hydraed = Dec. adh
Dehydrated = Inc. adh

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4
Q

Regulates **sodium ** reabsorption in dct

A

Aldosterone

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5
Q

Process

Angiotensinogen > renin > angio I > ace > angio II - effects?

A
  1. Inc. na and water reabsorption
  2. vasoconstriction (inc. blood flow)
  3. correct renal blood flow

JG cells - prod. renin
Macula densa - detects dec. in bp

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6
Q

Functions:
* regulates acid-base bal. thru hydrogen secretion (ammonium (nh4), dihydrogen phosphate (h2po4)
* eliminates waste prod not filtered by glomerulus

A

tubular secretion

renal tubular acidosis - failed prod of acid in urine due to inability to secrete hydrogen ions

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7
Q
  1. Evaluate glomerular filtration - able to remove filterable substance from blood
  2. Most common
  3. Gold std
  4. Marker - renal tubular function
A
  1. Clearance
  2. Creatinine
  3. Insulin
  4. Beta-microglobulin
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8
Q
  1. Detect and monitor kidney dse
  2. Dis mtd developed by
A
  1. eGFR
  2. cockgroft and gault

modification of diet in renal dse - Isotope dilution mass spectrophotometry (mdrd-idms) - reco. by National kidney dse education program

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9
Q
  1. Evaluate tubular reabsorption
    test:
  2. use number and density of particles in soln
  3. use number of particles in soln
A
  1. Concentration
  2. SG
  3. Osmolality (preferred)

Obsolete
1. Fishberg
2. Mosenthal

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10
Q

Test for both secretion and renal blood flow - most commonly use; reference mtd

A

p-aminohippuric acid (pah)

Obsolete
* penlsulfonpthalein (psp)

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11
Q
  1. First illustrated medical book printed - urine wheel
  2. Blood
  3. Yellow bile
  4. Phlegm
  5. Black bile
A
  1. Johannes de kethams fasciculus medicinae 1491
  2. sanguineous
  3. choleric
  4. phlegmatic
  5. melancholic
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12
Q

Albuminuria - boiling water

A

Frederik dekkers

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13
Q

Uroscopy, Sputum exam

A

Hippocrates

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14
Q

Book - pisse prophets

A

thomas bryant

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15
Q

urine sediment

A

thomas addis

addis count

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16
Q

UA - doctor’s routine exam

A

richard bright

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17
Q

urochrome

A

ludwig thudichum

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18
Q

CFS

A

domenico cotugno

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19
Q

phenylketonuria

A

ivan folling

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20
Q

alkaptonuria

A

archibald garrod

21
Q

Orthostatic/cylic proteinuria

A

frederich willian pavy

22
Q

cystine calculi

A

willian wollaston

23
Q
  1. Organic compound of urine
  2. Inorganic
A
  1. Urea > Crea
  2. Cl > Na > K > NaCl (principal salt)

60g = 24 hrs

24
Q

Collection

Cytology
1. Ideal
2. Preferred

A
  1. Random
  2. 1st morning
25
# Collection Diabetes 1. Screen/Monitor 2. Diagnosis
1. 2hr post prandial 2. Fractional specimen (2 - series)
26
# Collection Glucose 1. Determination 2. Screen
1. 2nd morning 2. 2hr post prandial
27
# Collection Prostatic infection
1. 3 glass tech 2. Stamey-Meares (4 glass) ## Footnote Prostatitis
28
# Collection Orthostatic proteinuria
1st morning
29
addis ct
12 hr urine
30
Nitrite/1st morning detr.
4 hrs ## Footnote Urine stayed 4 hrs before voiding
31
Urobilinogen
afternoon 2-4pm
32
adultered specimen
pH >9 SG < 1.005 ## Footnote Blueing agent -added to toilet water, avoid adulteration
33
Least affected in unpreserved urine
Protein ## Footnote Dec rbc/wbc - disintigrate in dilute alkaline urine
34
# Preservative * Precipitates amorphous phosphates and urates * For ua, culture (inhibits bacterial growth 24hrs)
Refrigeration ## Footnote Gray C & S tube - 48hrs inhibit bacterial growth
35
# Preservative * Preserves protein * Bacteriostatic * 5-hiaa * Culture transport
Boric acid
36
Sediment preservative thus, addis ct
Formalin
37
* Floats and clings preservative * Best all around preservative
Toluene
38
# Preservative 1. Prevents glycolysis but it inhibits strips 2. Alternative
1. Sodium flouride 2. Sodium benzoate ## Footnote *drug analysis*
39
Refrigeration is not possible
Tablet
40
Preservative - odor change
Phenol
41
# Preserative * Preserves cellular elements * For cytology studies
Saccomanno fixative ## Footnote 50% ethanol + 2% carbowax
42
Brown black urine
1. Methemoglobin 2. Homogentisic acid - alkaptunuria 3. melanin - air exposure 4. fava beans - cola
43
purple urine
indican - kleb. and providencia
44
green urine
* pseudomonas * phenol
45
blue green urine
* phenol * blue diaper syndrome - hartnup dse
46
1. tea colored urine w/ yellow foam 2. orange, viscous w/ yellow foam 3. organge yellow no yellow foam
1. bilirubin 2. phenazopyridine 3. urobilin
47
Soluble w/ heat ## Footnote Acidic
* Amorphose urates * uric acid
48
Soluble - Dilute acetic acid ## Footnote Alkaline
* rbc * amorphose phosphates * carbs ## Footnote Insoluble * livings: bacteria, yeast, spermatozoa * wbc