CMN 568 - Unit 1 Antibiotics Flashcards Preview

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Flashcards in CMN 568 - Unit 1 Antibiotics Deck (17):
1

First line treatment for AOM

Amoxicillin 80-90mg / kg / day BID for:
< 2 years with severe symptoms - 10 days
2-6 years mild-mod symptoms - 7 days
> 6 years with mild-mod symptoms - 5 days

NTE 4 g / day

2

If unable to take oral Antibiotics for AOM

Ceftriaxone (Rocephin) 50 mg / kg IM for 1 to 3 days

3

If patient develops papular rashes / hives from Amoxicillin (PCNs)

1. Cefuroxime (Ceftin)
2. Cefpodoxime (Vantin)
3. Cefdinir (Omnicef)
4. Rocephin (Ceftrioxine) IM 50mg / kg / day for 1 to 3 days

4

If patient develops severe allergic reaction from Amoxicillin (PCNs)

1. Triamthoprin-Sulfamethoxazole (Bactrim)
2. Azithromycin
3. Erythromycin
4. Clarithromycin
5. Clindamycin with or without ceftriaxone

5

What to consider with using Macrolides for prescribing

Consider that Macrolides are usually ineffective in Drug-resistant Strep Pneumoniae and H. Flu, especially as winter progresses

6

Second line treatment for AOM or If patient has had antibiotic in the last month, or does not improve in 48-72 hours on Amoxicillin, or has otitis-conjunctivitis syndrome

1. Amoxicillin-Clavulonate ES (Augmentin) 90 mg / kg / day BID
2. Rocephin (Ceftrioxine) IM 50mg / kg / day for 1 to 3 days
3. Cefuroxime (Ceftin)

7

Antibiotic treatment for OME

No antibiotic necessary

8

First line treatment for Otitis Externa

1. Fluoroquinilones with steroid (Ciprodex) ottic drops 3-4 gtts BID for 7 days

9

Second line treatment for Otitis Externa

1. Neomycin / Polymxin B / Hydrocortisone 3-4 gtts TID-QID for 7 to 10 days

CAUTION: Not to be used if TM is perforated

10

Penicillin V and Benzathine (Bicillin) dosage for GABHS Pharyngitis if LESS than 27 kg

1. Penicillin V 250 mg BID to TID for 10 days
2. Benzathine IM 600,000 units

11

Penicillin V and and Benzathine (Bicillin) dosage for GABHS Pharyngitis if MORE than 27 kg

1. Penicillin V 500 mg BID to TID for 10 days
2. Benzathine IM 1.2 Million units

12

Antibiotic considerations for GABHS Pharyngitis

1. Amoxicillin 50 mg / kg / day BID for 10 days NTE 1200 mg total dose
2. Cephalexin 25-50mg / kg / day BID for 10 days
3. Clindamycin 20 mg / kg / day TID for 10 days (Allergies to PCN)
4. Azithromycin 12 mg / kg OD for 5 days NTE 500 mg / day

13

First line treatment for Acute Bacterial Rhinosinusitis (ABRS)

1. Amoxicillin
2. Amoxicillin-Clavulonate (Augmentin)

14

Treatment for ABRS if with mild and severe allergic reaction to penicillin

1. Mild - Cefuroxime or Cefpadoxime
2. Severe - Clindamycin or Linezolid

15

Second line treatment for ABRS or if no improvements for 48-72 hours

1. Augmentin
2. Cehpalosphorin

16

Treatment for Chlamydia and N. Gonorrhea conjunctivitis

Will need systemic antibiotic

17

Treatment of Bacterial Conjunctivitis

1. Erythromycin ophthalmic ointment: Apply 0.5-in ribbon QID for 5-7d
2. Polymyxin-trimethoprim ophthalmic solution: Instill 1-2 drops QID for 5-7d
3. Sulfacetamide ophthalmic solution: Instill 1-2 drops QID for 5-7d
4. Azithromycin ophthalmic solution: Instill 1-2 drops BID for 2d, then 1 drop for 5d
5. Ciprofloxacin ophthalmic solution: Instill 1-2 drops every 2h while awake for 2d, then 1 or 2 drops every 4h while awake for the next 5d
6. Levofloxacin ophthalmic solution: Instill 1-2 drops in affected eye(s) every 2h while awake (up to 8 times daily) on days 1-2; instill 1-2 drops in affected eye(s) every 4h while awake (up to 4 times daily) on days 3-7
7. Ofloxacin ophthalmic solution: Instill 1-2 drops in affected eye(s) every 2-4h on days 1-2; instill 1-2 drops QID on days 3-7