CN VIII: Vestibulocochlear Flashcards

(30 cards)

1
Q

Inner ear embedded in which cranial bone?

A

temporal

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2
Q

Two portions of inner ear and associated fluids

A
membranous inside bony labyrinth (for vestibular) or cochlea (for auditory)
Membranous: 
   -endolymph: low Na, high K
   -hair cells
Bony:
   -perilymph: high Na, Low K
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3
Q

endolymph path

A
  • produced in membranous labrinth
  • leaves via endolymphatic duct
  • to endolymphatic sac in dura
  • reabsorbed into venous system
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4
Q

vestibule

A

central enlarged region of bony labrynth

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5
Q

ampullae

A

dilation at one end of each semicircular canal closest to utricle

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6
Q

pairs of semicircular canals

A

L and R horiz
L post and R ant
L ant and R post

-Because they’re in the same plane

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7
Q

Utricle/Saccule

A

Utricle is horizontal
Saccule is vertical

  • detect linear acceleration in their plane and info on static head position
  • in bony vestibule
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8
Q

Kinocilium

A
  • next to tallest hair cell
  • only important for development
  • oriented towards utricle in horizontal canals (opposite in ant/post canals)
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9
Q

Vestibular hair cells (semicircular canals)

structure/location

A
  • apical stereocilia into endolymph
  • release glutamate to CN VIII basally
  • in cristae in ampullae
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10
Q

Vestibular hair cells

on/off

A
  • bending towards kinocilium ON, away is OFF
  • on via mechanically gates K channels-> K into cell-> VG Ca channels open -> glutamate released
  • Note: always baseline NT release
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11
Q

Cristae

A
  • in ampullae of semicircular canals
  • hair cells embedded in cupula
  • cupula extends width of ampulla

—>endolyph will move in OPPOSITE direction of rotation

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12
Q

Vestibulo-ocular reflex

pathways

A
  • allow fixation on object when head is moving
  • in from sensory afferents in ear
  • out bilaterally to abducens, throchlear, occularmotor nuclei for eye movement via MEDIAL LONGITUDINAL FASCICULUS
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13
Q

Maculae

A
  • location of hair cells in utricle/saccule (1 in each)

- hair cells embedded in otolithic membrane containing otoconia/otoliths (carbonate crystals)

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14
Q

Striola

A
  • line in macula which hair cells are aligned along
  • arranged such that any movement causes excitation of some hair cells and inhibition of others.
  • bean shaped
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15
Q

Vestibulo thalamo-cortical pathway

A

lateral and superior vestibular nuclei project to VPL of thalamus -> parietal cortex -> near the face representation of post central gyrus

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16
Q

Vestibulo-ocular reflex

left rotation, response

A
  • L rotation of head
  • Excitation of L horizontal semicircular canal
  • Increase contraction of L medial rectus and R lateral rectus
  • Decrease contraction of L lateral rectus and R medial rectus
17
Q

Auricle

A

AKA pinna

outer ear

18
Q

muscles of middle ear

function, attachement, CN

A
  • to dampen vibrations
  • tensor tympani
    • attached to malleus (CN-V)
  • stapedius
    • attached to stapes (CN-VII)
19
Q

What kind of joints connect the ossicles?

20
Q

Cochlear duct

A

AKA membranous cochlea

21
Q

Helicotrema

A

turn or ‘end’ of cochlea where perilymph reverses direction down the other side of the cochlear duct

22
Q

vestibular membrane

A

top membrane of cochlear duct (closest to oval window)

23
Q

basilar membrane

location/function

A
  • bottom membrane of cochlear duct (closest to round window)
  • location of organ of corti
  • stiff at cochlear base (by oval and round windows)
  • flexible at cochlear apex
24
Q

Scala vestibuli vs media vs tympani

A
  • scala vestibuli: space above cochlear duct
  • scala media: space inside cochlear duct (triangular)
  • scala tympani: space below cochlear duct
25
osseous spiral lamina
bony projection into the cochlea
26
Auditory hair cells | structure/location
- apical stereocilia project into endolymph in cochlear duct - stereocilia tips embedded in tectoral membrane (outer hair cells) - basal NT release to CN VIII
27
How does cochlea distinguish high vs low notes?
differences in basillar membrane stiffness stiff at base for high notes flexible at apex for low notes TONOTOPICALLY ORGANIZED
28
Auditory pathway
Cochlea -> spiral/cochlear ganglion -> cochlear nucleus/pontomedullary jxn -> BILATERAL to superior olive (majority decussate via trapazoid body) -> Inferior colliculus via lateral lemniscus -> medial geniculate nucleus in thalmus -> auditory cortex (A1;41/42) Note: some neurons bypass the superior olive and go straight from cochlear nucleus to inferior colliculus
29
How does brain distinguish location of sound?
Brain compares differences in synaptic timing between fibers travelling from cochlear nucleus to superior olive directly and those decussating along trapazoid body (and compares for input from both ears)
30
Where do auditory fibers cross contralaterally? (3)
- trapezoid body - inferior colliculus - medial geniculate nucleus