Cns Flashcards

(65 cards)

1
Q

repeated question about hypoglossal nerve injury what is the sign?

A

deviation of tongue to the side of the lesion

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2
Q

What is the most injured nerve in case of thrombosis in cavernous sinus?

A

Trochlear

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3
Q

Lesions to the anterior limb of the internal capsule result in what?

A

Aphasia

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4
Q

what is lost in ischaemia reperfusion cycle

A

Oxidative phosphorylation

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5
Q

diseases that have CGG and loss of function mutation ?

A

Fragile X

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6
Q

thalamus contralateral hemiparesis neglect

A

Intralaminar

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7
Q

A Drug was given to a lady after surgery and she lost consciousness and resulted in
hypotension?

A

Codeine

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8
Q

Patient symptoms were referring to meningitis i think or encephalitis , there was
meningeal irritation , he was in his 70’s , asking which empirical therapy u would
give?

A

Vancomycin ceftriaxone and ampicillin (he is >65 )

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9
Q

Into what structure do auditory afferents travel in the midbrain

A

lateral lemniscus

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10
Q

70 Mutation of HNA?

A

FXR

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11
Q

After taking 3 doses of covid vaccine a patient experienced a loss of sensation
symmetrical in the lower limb then it involved the upper limb ? He is a smoker and
recently diagnosed with type 2 diabetes and is on oral therapy. He has back pain and
was prescribed NSAIDS. On physical examination, he showed loss of deep tendon
reflex.

A

Peripheral demyelination

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12
Q

Pt died of acute lobar pneumonia and suffered a neurological disease (it said that
she was suffering from these neurological for a long time before) she is hypertensive
and autopsy reveals brown deposit in periventricular white white matter. What is most
likely cause for the changes seen
a. Septic infarcts to brain

A

She has ms

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13
Q

Patient is acting on his dreams + anosmia ?

A

lewy body dementia

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14
Q

What describes carpal tunnel

A

Mononeuropathy

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15
Q

75 A 78 year old right-handed male collapses and is brought from an accident to
emergency. He seems to follow clear one-step commands but he gets very frustrated
as he cannot answer questions. He is unable to lift his right hand or leg.his blood
pressure is 149/87. He takes only aspirin and furosemide. What is the most likely
diagnosis?

A

Left cortical hemorrhage

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16
Q

What connects the temporal lobes?

A

anterior commissure

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17
Q

An old lady was admitted to hospital, she was eating her lunch then suddenly
dropped the fork . She calls for the nurse who notices the left side of her face is
drooping, What is the best next course of action?

A

Urgent CT

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18
Q

What is true about stereocilia?

A

tips mediate mechanoelectrical transduction (MET)

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19
Q

Hair cell contract by what

A

K+ influx

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20
Q

What does the sulcus limitans separate

A

motor & sensory nuclei

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21
Q

During childbirth, an excessive anteroposterior compression of the head may tear the
anterior attachment of the falx cerebri from the tentorium cerebelli. The bleeding that
follows is likely to be from which of the following venous sinuses?

A

Straight sinus

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22
Q

Which part of the cerebellum is affected in the following test?

A

Cerebrocerebellum

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23
Q

Which structure is least affected by herniation of the uncus thru transtentorial notch?

A

MCA

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24
Q

Which one is not affected by pica infarction ?

A

Medial longitudinal fasciculus

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25
What would be affected in disorders of brain peroxisomes ?
degradation of glycosphingolipids
26
Which mutation leads to leber’s congenital amaurosis ?
RPE-65
27
Identical twins have develop MS by which percent does they develop it ( something like that) one twin got MS what is the chance of the other monozygotic twin from getting it)
25 - 30%
28
19 years old women present unconscious with lumbar CSF sample low glucose normal protein associated with medial temporal lobes on both sides
HSV encephalitis
29
29. 3 yo with multiple types of seizures, absence, tonic-clonic etc, with slow waves and spikes
Lennox gastaut
30
They gave CSF parameters and it was bacterial meningitis
Exudate over cortex
31
a patient had a cardiac arrest & post-mortem examination showed a diffuse pattern of cortical injury ,what is the most probable etiology?
global cerebral ischemia
32
Physio question zorans note on balance, what causes activation of anterior tibialis, abdomen, and quadriceps
Forward translocation of base longer than feet
33
What is Sativex used for?
MS
34
Question about someone who had difficulty in understanding speech, where is the lesion (i think wernicke area)
Superior temporal gyrus understanding speech= wernicke producing speech= broca (frontal)
35
a person came with a head injury. What is affected in medial orbital wall fracture?
Nasociliary nerve
36
Cardinal features of parkinsons
Bradykinesia, Resting tremor, instability, Rigidity
37
physio question about balance zoran’s note - what is involved in maintaining posture when the head is accelerated and moved
lateral vestibular
38
Question about a Kuwaiti lady who had a new onset of seizures and two ring enhancing lesions on CT, and they suspect a parasitic infection how would you confirm diagnosis?
Immunoblot Cysticercosis is an infection caused by the larvae of the parasite Taenia solium. This infection occurs after a person swallows tapeworm eggs. The larvae get into tissues such as muscle and brain, and form cysts
39
Which organism needs chemoprophylaxis for close contacts
Neisseria Meningitidis
40
Elderly patient had an injury occipital region, resulting in many fissure fractures in that area, what is most likely
Subdural hemorrhage
41
Patient taking fluoxetine has surgery and was given a drug to relieve pain but caused serotonin syndrome
Tramadol
42
What makes a person enter the N2 stage ?
sleep spindle and k complex
43
Donepezil is prescribed to Alzheimer’s patients,which increases the Ach levels, what can be seen in normal individuals?
Inhibit non REM chE inhibitors
44
INNOVAR constitutes what type of drugs?
D2 antagonist and u-opioid agonist mind surgeries -aware shway
45
Classic Michael Jordan picture from the note, What cells are involved in reducing background noise?
Wide amacrine cells
46
stepping on a sharp object causes flexion of the leg on that side. What happens to the leg on the other side?
an inhibitory interneuron synapses with motor neuron innervating the flexor muscle of the leg other side
47
Bilateral injury to posterior parietal lateral lobe, rostrum to primary visual cortex?
cannot reach objects
48
What will happen i if you rotate baby’s head to the right (without titling)
right limbs extend, left limbs flexed
49
What is involved in center surround image processing?
Idk
50
Question about what does dopamine do in affecting basal ganglia
Something along the lines of inhibiting Gpi
51
PDE Drugs that affect cGMP in the eye, what do they have an effect on?
Loss of light,darkness differentiation
52
Cause of CSF flow
Making new CSF
53
Pathogenesis of alzheimer's disease in relation to Tau and AB42 fibres
Inflammatory response causing phosphorylation of Tau
54
What vaccine is given before going to Hajj?
A,B,C and W135
55
what drug is given orally daily to improve alzheimer's cholinergic activity
Donepezil
56
A 23 year old with double vision and diplopia which of the following investigations indicates myasthenia gravis
decremental response to repetitive stimuli
57
A 50 year old female with neurological symptoms and had gastric bypass surgery what is the cause of the neurological symptoms?
B12 deficiency
58
how does prpsc affect the normal prion prp
Causes conformational change of normal protein
59
Question which of the following are 3rd gen cephalosporin
Cefuroxime
60
which drug causes pseudomembranous colitis
C.difficile
61
we dont recall the question but the answer was thalamus ventral lateral nucleus. it probably had to do witj movement or the basal gangla. (i think it was repeated, choreiform movemet)
we dont recall the question but the answer was thalamus ventral lateral nucleus. it probably had to do witj movement or the basal gangla. (i think it was repeated, choreiform movemet)
62
repeated diagnostic test for narcolepsy
multiple sleep latency test
63
location of cochlear nucleus repeated
Inferior to ICP
64
quick hyponatremia treatment >> central pontine demyelination
quick hyponatremia treatment >> central pontine demyelination
65
What is likely diagnosis of someone with loss of sensation and weakness first in the arms and back, and then become worse and spread to legs
central cord syndrome