CNS Flashcards

(38 cards)

1
Q

intracranial HTN cut off

A
  1. 40 is severe(ischemia)
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2
Q

signs of elevated ICP

A

HA/nausea then decreasing consciousness then coma/cushing response and motor posturing

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3
Q

normal ICP

A

5-10

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4
Q

cerebral auto regulation range

A

50-150

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5
Q

cerebral steal

A

vasodilation that occurs in healthy region of brain during period of ischemia. so pulls blood flow from ischemia to healthy brain. so ischemia gets even worse blood flow.

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6
Q

inverse cerebral steal/robin hood

A

vasoconstriction caused by hyperventilation or drug that causes vasoconstriction in healthy area to have more flow go to ischemia area

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7
Q

how much oxygen and glucose does brain get over needed

A

3x oxygen and 7x glucose during normal activity

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8
Q

CBF numbers

A

50mL/100g/min. gray matter is 80, white is 20

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9
Q

CBF per min

A

750mL/min

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10
Q

CBF ischemia numbers by 100g

A

20-30 start of neuro symptoms. 15-20 isoelectric EEG, no evoked potentials. 10-15 Na/K pump fail, cytotoxic edema. less than 10 is irreversible damage

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11
Q

CSF volume

A

124-150mL

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12
Q

CSF production per hour

A

20-30cc

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13
Q

what makes CSF

A

choroid plexus ependymal cells

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14
Q

pH of CSF

A

7.32

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15
Q

IV anesthetics that stand out brain

A

ketamine up CBF. etomidate can precipitate seizure

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16
Q

worst volatile that causes cerebral vasodilation mor

A

halothane. best is sevo

17
Q

volatile that is epileptogenic

18
Q

volatile we use that up CBF

A

des over 1 MAC

19
Q

PaCO2 goal for craniotomy

A

linear relationship between PaCO2 and CBF from 30-60. under 30 no change so keep at 30

20
Q

how many vertebrae

21
Q

how many spinal nerve pairs

22
Q

which tract crosses in cord

23
Q

how to know where autonomic dysreflexia starts

A

happens w/ injury above T6. flushing above injury(parasympathetic) and vasoconstriction below(sympathetic

24
Q

collateral spinal blood flow worst where

25
which system has ganglia in the organ
parasympathetic
26
sympathetic chain in cord location
T1 to L2
27
what nerves have acetylcholine
all parasympathetic and pre ganglionic sympathetic
28
a1 receptor job
vascular smooth muscle constriction
29
a2 receptor job
found on pre synaptic neuron and inhibit release of norepi
30
b1 receptor job
up contractility and HR. too much can cause arrhythmia
31
b2 receptor job
vascular and non vascular smooth muscle relaxation
32
alpha brain wave
Awake-resting
33
beta brain wave
Busy, thinking
34
theta waves
GETA. general anesthesia
35
delta waves
Deep sleeping-general anesthesia
36
anesthetic agents other than increase latency/decrease amplitude. SSEP
NO latency no change, down amp. etomidate up both. ketamine up amp. opioid and muscle relaxant no changes
37
type of greatest heat loss during GA
radiation
38
factors that are synthesized in liver
2, 5, 7, 9, 10, 11 and 12