CNS:ANTICONVULSANT Flashcards

(28 cards)

1
Q

Diverse groups of pharmocological agents used to treat epileptic seizures

A

anticonvulsants

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2
Q

sudden burs tof uncontrolled electrical activity that occurs in the brain when there is excessive activity

A

seizure

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3
Q

localized:
generalized:

A

one side of the brain: both sides of the brain

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4
Q

what is the mechanism of action of anticonvulsants

A
  1. blocks ion gated sodium and calcium channels
  2. inhibit action potential firing
  3. inhibit glutamate production
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5
Q

blocks both sodium and calcium channels

A

zonisamide, valproic acid, topiramate and lamotrigine

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6
Q

blocks sodium channels only

A

phenytoin, oxcarbazepine, carbamazepine

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7
Q

blocks 2 delta subunits

A

pregabalin, gabapentin

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8
Q

NMDA binds to

A

calcium

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9
Q

Sodium binds to

A

AMPA

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10
Q

blocks calcium channels

A

leviteracitam, felbamate, benzodiazepines, barbiturates, tiagabine, gigabatrin

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11
Q

blocks NMDA receptors

A

felbamate

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12
Q

it inhibits gaba reuptake

A

tiagabine

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13
Q

inhibits GABA transferase

A

vigabatrin

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14
Q

sedation and diziness is not common in anticonvulsant drugs, T or F

A

false

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15
Q

low sodium or hyponatremia is caused by what drugs

A

oxcarbazepine and carbamazepine

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16
Q

gingival hyperplasia and hirsutism is caused by what drug

17
Q

vigabatrin causes double vision T or F

A

F- loss of vision

18
Q

lamotrigine

A

double vision

19
Q

topiramate causes

20
Q

weight gain and peripheral edema is caused by

A

valproic acid, gabapentin, and pregabalin

21
Q

topiramate and zonisamide causes

A

cognitive problems

22
Q

felbamate and valproic acid

A

liver toxicity

23
Q

NEUROLOGICAL DISORDER THAT RESULTS IN A PROGRESSIVE LOSS OF COORDINATION AND MOVEMENT

A

parkinsons disease

24
Q

sends dopamine to help coordinate brain inputs

25
relays sensory information and plans for future action
neocortex
26
responsible for movement
striatum
27
precursor of dopamine
levodopa
28
precursor of levodopa
tyroxine hydroxylase