cns infection Flashcards
(17 cards)
What layers make up the leptomeninges?
arachnoid and pia
group b strep
- ecoli
- l.monocytogenes
- h influenza (unimmunized infants)
cause meningitis in neonates
what causes meningitis in kids?
n. meningitidis
- coxsakievirus
what causes meningitis in adults?
s. pneumoniae
what causes meningitis in immuno compromised?
fungi
what presents with these symptoms
head ache, rigidity, fever
-photophobia, vomiting, altered mental status
symptoms of meningitis
What are the differences between the csf of bacterial and viral meningitis?
bacterial: white, neutrophils, inc protein, dec glucose
viral: clear, lymphocytes, normal protein, normal glucose
how do bacterial infections become abscess?
due to direct implantation
- hematogenous spread
- local extension (adjacent)
what is the composition of CSF in a pt with brai abscess
inc wbc and protein
glucose is normal
what causes encephalitis?
viral infection
What presents with negri bodies?
- pt presents with cns excitability, violent motor convulsions
- death from repiratory failure
rabies
viral infection that…
-present perivascular inflammatory infiltrates
-cowdry type a bodies found in neurons and glial cells
herpesvirus
viral infection that….
-presents with microcephaly w/ periventricular calcification in neonates
CMV
degeneration due to prions
- converts normal protein
- damages neurons and glial cells
- intracellular vacoules
Transmissible spongiform encephalopathies (TSE)
=CJD, kuru, gss, ffi
which TSE is trasmitted by eating brains of a carrier?
kuru
which TSE is a sleep disorder with pathological lesions in the thalamus?
fatal familial insomnia (FFI)
which TSE presents with slowly progressive ataxia and dementia
-has widespread abnormal prion amyloid plaques throughout the cns
gerstmann straussler scheinker syndrome (GSS)
