coagulation and anti-coagulation

Question 1

primary haemostasis

Answer 1

platelet plug

Vwf useful in arterial beds and high flowing vessels

Question 2

secondary haemostasis

Answer 2

fibrin formation and coag cascade ( factor VIII is a co-factor - cataylst that holds)

Question 3

3 haemophilias - ABC what factors

Answer 3

8.9,11

Question 4

D-dimer raised when

Answer 4

malignancy, infection , pregnancy, DVT , PE

Question 5

wells score above what for DVT

Answer 5

2

4 for PE

Question 6

positive D-dimer negative USS how to manage

Answer 6

repeat d-dimer 1 week later

Question 7

most likely time to get a dvt when pregnant

Answer 7

6w post partum

Question 8

potentiate the action of antithrombin III

Answer 8

heparin in particualrunfractioned

Question 9

when might you thrombolyse a DVT

Answer 9

acute ischaemi a

Question 10

what section of people with thrombotic problems can you not give DOAC too

Answer 10

antiphospholipid syndrome - they need warfarin for secondary prevention

Question 11

what type of pain relief medications would you avoid in DVT

Answer 11

NSAID

Question 12

remember to suggest to change contraceptive method in DVT prevention

Answer 12

COCP –> POP

Question 13

where does most of your Vitk come from

Answer 13

gut bacteria - which is why you give Vit k deficiency when have abx

Question 14

infection raises what

Answer 14

platelets - DIC? - will need to check