Coagulation Meds

Question 1

Alteplase brand name?

Answer 1

Activase

Question 2

What is Cathflo Activase?

Answer 2

Can be used to flush clogged IV or arterial lines.

Question 3

Activase indications?

Answer 3

MI, stroke

Question 4

What is the half-life of Alteplase?

Answer 4

5-min

Question 5

Clopidogrel brand name?

Answer 5

Plavix

Question 6

Most common ADP inhibitor?

Answer 6

Clopidogrel (Plavix)

Question 7

Clopidogrel route?

Answer 7

Oral

Question 8

Clopidogrel interactions?

Answer 8

NSAIDS
amiodarone
calcium channel blockers
PPIs

Question 9

Clopidogrel (Plavix) category?

Answer 9

Antiplatelet

Question 10

Alteplase category?

Answer 10

Thrombolytic

Question 11

Aminocaproic acid brand name?

Answer 11

Amicar

Question 12

Amicar route?

Answer 12

Oral/parenteral

Question 13

Amicar category class?

Answer 13

Thrombolytic
(Synthetic antifibrinolytic)

Question 14

Amicar expected action?

Answer 14

Prevent/control excessive bleeding

Question 15

Dabigatran brand name?

Answer 15

Pradaxa

Question 16

Dabigatran route?

Answer 16

Oral

Question 17

Dabigatran is a prodrug that becomes activated in…?

Answer 17

The liver

Question 18

Argatroban route?

Answer 18

IV only

Question 18

Dabigatran adverse effects?

Answer 18

Bleeding, GI bleeding

Question 18

Dabigatran dose is dependant on…?

Answer 18

Renal function

Question 18

Dabigatran antidote?

Answer 18

IDARUCIZUMAB (PRAXBIND)

Question 18

Dabigatran is the first oral…?

Answer 18

Direct thrombin inhibitor

Question 18

Argatroban use?

Answer 18

Active HIT and percutaneous coronary intervention procedures in patients at risk for HIT

Question 19

Argatroban category class?

Answer 19

Synthetic direct thrombin inhibitor

Question 20

Apixaban brand name?

Answer 20

Eliquis

Question 21

Apixaban use?

Answer 21

Uncontrollable bleeding

Question 22

Apixaban category class?

Answer 22

(Anticoagulant) Specific antidote factor XA inhibitor

Question 23

Apixaban black box warning?

Answer 23

Thromboembolic events

Question 24

Aspirin category class?

Answer 24

Antiplatelet

Question 25

Aspirin contraindications?

Answer 25

Flulike symptoms in teens and children, Reye's syndrome

Question 26

Enoxaparin brand name?

Answer 26

Lovenox

Question 27

Enoxaparin route?

Answer 27

Injectable

Question 28

Enoxaparin category class?

Answer 28

Parenteral anticoagulant

Question 29

Enoxaparin use?

Answer 29

Prophylaxis and treatment

Question 30

Do not do this to enoxaparin.

Answer 30

Expel the air bubble in pre-filled syringes.

Question 31

Heparin can cause....?

Answer 31

Thrombocytopenia (HIT)

Question 32

Heparin category class?

Answer 32

Anticoagulant

Question 33

Heparin expected action?

Answer 33

Inhibit clotting factors II (Thrombin) and XA

Question 34

Type I HIT

Answer 34

Gradual reduction in platelets Heparin therapy can generally be continued

Question 35

Type II HIT

Answer 35

Acute fall in the number of platelets (>50%) Discontinue heparin therapy

Question 36

Treatment of HIT?

Answer 36

Argatroban/lepirudin

Question 37

Heparin complications?

Answer 37

Melena, hematuria, petechiae, ecchymoses, gum/mucous membrane bleeding

Question 38

Rivaroxaban brand name?

Answer 38

Xarelto

Question 39

Rivaroxaban is the first oral..?

Answer 39

Factor XA inhibitor

Question 40

Rivaroxaban use?

Answer 40

Prevention of strokes in patients with A-Fib Post-op thromboprophylaxis Treatment of DVT and PE

Question 41

Rivaroxaban complications?

Answer 41

Dizziness, peripheral edema, headache, bruising, diarrhea, hematuria, bleeding

Question 42

Rivaroxaban category class?

Answer 42

Anticoagulant

Question 43

Warfarin contraindications?

Answer 43

Pregnancy

Question 44

Warfarin complications?

Answer 44

Skin necrosis, purple toes syndrome

Question 45

Warfarin brand name?

Answer 45

Coumadin

Question 46

Treatment for Warfarin toxicity?

Answer 46

10 mg of Vitamin K within 6 hours

Question 47

Warfarin category class?

Answer 47

Oral anticoagulant