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week 11 > Coeliac disease > Flashcards

Coeliac disease Flashcards

1
Q

Signs and symptoms of coeliac disease?

A
  • Chronic/ intermittent diarrhoea
  • Failure to thrive
  • Persistent gastro symptoms with fatigue
  • Recurrent abdo pain
  • Unexplained iron deficiency anaemia
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2
Q

Serology testing for coeliac disease?

A

Tissue transglutaminase (TTG) antibodies 1st choice (>10U/ml = coeliac)
and
Total IgA levels

second line- anti EMA

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3
Q

Always test for coeliac disease in new onset of which 2 autoimmune conditions?

A
  1. Type 1 diabetes
  2. Thyroid disease
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4
Q

Inflammation affects where?

A

Small bowel- jejunum

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5
Q

Which 2 genotypes is coeliac disease associated with?

A

HLA-DQ2 and HLA-DQ8

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6
Q

Skin issue caused by coeliac disease?

A

Dermatitis herpetiformis- itchy blistering skin rash typically on abdo

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7
Q

Endoscopy findings in coeliac disease?

A

Crypt hyperplasia
villous atrophy

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week 11 (2 decks)

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