Colon & Rectum Flashcards

(189 cards)

1
Q

Foregut structures extend all the way to?

A

2nd part of duodenum

rely on celiac artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Midgut structures of abdomen?

A

extends from duodenal ampulla to distal tranverse colon (rely on SMA)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hindgut structures?

A

distal third of t-colon, descending colon, rectum

rely on IMA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Avg. diameter and length of cecum?

A

diameter is 7.5 cm

length approx. 10 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Acute dilatation of cecum greater than what number can result in acute ischemic necrosis and bowel perforation?

A

> 12 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Most common location of appendix in relation to the cecum?

A

retrocecal 65% of time

pelvic 30% of time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

These two parts of the colon are retroperitoneal in nature:

A

ascending + descending colon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How do we mobilize the colon and its mesentery from the retroperitoneum?

A

dissect along the white line of Toldt

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the white line of Toldt?

A

represents the fusion of the mesentery with the posterior peritoneum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What ligaments tether the colon to the hepatic flexure and the splenic flexures?

A

hepatic flexure; nephrocolic ligament

splenic flexure; phrenocolic ligament

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How do we get to the splenic flexure when mobilizing the colon?

A

dissecting the descending colon upward via white line of Toldt

then lesser sac is entered by reflecting the omentum away from t-colon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Attached to anterior surface of t-colon is greater omentum, which has how many layers?

A

fused double layer of parietal and visceral peritoneum (4 layers)

contains stored fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

The descending colon, lies ventral to left kidney and extends downward for how long?

A

25 cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Where do we see a transition from the thin walled, fixed, descending colon to the mobile sigmoid colon?

A

level of pelvic brim

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

In relation to the sigmoid colon, it has a long floppy mesentery, often attached to left pelvic sidewall, producing a small recess called the intersigmoid fossa, often a landmark for what?

A

left ureter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Rectum along with sigmoid serve as what?

A

fecal reservoir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

The rectum is usually 12-15 cm in length usually lacks what?

A

tenia coli and appeploic appendages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Why do we say the rectum posterior surface is almost completely extraperitoneal?

A

its adherent to presacral soft tissues, thus outside the peritoneal cavity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Anterior surface of proximal third of rectum covered by visceral peritoneum, what is this anterior space called?

A

Pouch of Douglas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What’s the pouch of douglas?

A

recto-uterine pouch

can serve as site of drop mets from visceral tumors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What’s Bloomer’s shelf?

A

drop mets from visceral tumors can fall into the pouch of Douglas and form a mass there

often detected by digital rectal exam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Rectum possesses three curves or involutions, known as?

A

valves of Houston

have no function, don’t impede flow

usually lost after surgical mobilization of rectum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Mobilization of rectum leads to loss of the 3 rectal curves called the valves of Houston, thus adding how much extra rectal tissue?

A

approx. 5 cm

great for anastomosing in the pelvis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

The rectum is intimately close to the presacral fascia, but it is not directly adhered to it, what separates it?

A

posterior aspect of rectum covered by mesorectum and the mesorectum covered by a thin layer of investing fascia called fascia propria

fascia propria prevents direct rectal adherence to presacral fascia

serves as a bloodless plane for oncologic rectal surgery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What is Waldayer's fascia?
recto-sacral fascia thick fascia connecting the presacral fascia to the fascia propria of rectum at the level of S4
26
Why is Waldayer's fascia an important surgical landmark?
its division during dissection from abdominal approach leads to entry into deep retrorectal pelvis
27
What 3 muscles collectively termed the levator ani form the pelvic floor?
pubococcygeus iliococcygeus puborectalis
28
What muscle permits descent of feces?
relaxation of puborectalis straightens the anorectal angle and allows fecal descent contraction causes the opposite
29
Puborectalis is in a constant state of contraction or relaxation?
Contraction--> important for continence
30
Arterial supply to the foregut, midut and hindgut?
Celiac A--> foregut SMA--> midgut IMA--> hindgut
31
Anastomosis of SMA and IMA?
SMA ends at distal t-colon IMA begins at splenic flexure Marginal artery of Drummond forms a communication arcade between these two vessels along the mesentery of colon
32
SMA supplies what??
entire small bowel via 12-20 jejunal-ileal branches to the left 3 main colonic branches to the right (right colic, middle colic, ileo-colic)
33
Ileo-colic artery supplies?
terminal ileum cecum appendix (via appendicular branch)
34
The middle colic artery off of the SMA supplies what?
gives of left and right branch supplies proximal and distal T-colon
35
Griffith's point?
watershed area by splenic flexure, where left branch of middle colic off of SMA and left colic artery from IMA don't have a strong communication anastomosis usually avoided by splenic flexure due to tenuous blood supply
36
Where do we find the IMA anatomically?
level of L2-L3 | 3 cm above aortic bifurcation into iliacs
37
Branches off of IMA?
left colic artery sigmoid branches superior rectal artery
38
What is the arc of Riolan?
AKA meandering mesenteric artery | connects proximal SMA to proximal IMA
39
Meandering mesenteric artery, AKA arc of Riolan is what?
connects proximal SMA to proximal IMA
40
Blood supply of rectum?
superior rectal artery --> IMA middle rectal artery--> internal iliac A inferior rectal artery--> pudental artery--> internal iliac A
41
Venous drainage of right and proximal tranverse colon?
SMV (joins splenic vein to go into portal vein)
42
Distal t-colon, descending colon, sigmoid colon, and most of rectum drain via what vein?
IMVA (joins splenic vein)
43
Anal canal venous drainage?
drained by middle + inferior rectal veins empty into the internal iliac vein--> IVC
44
50% of fecal mass is comprised of?
bacteria
45
Most colonic bacteria are?
anaerobic species
46
Principle source of nutrition for colonocytes?
short chain fatty acids--> created by bacterial breakdown of starches
47
What species of bacteria predominate throughout the colon?
bacteroides species | e.coli, klebsiella, proteus, lactobacillus make up the rest
48
Unlike most of the mucosal lining of the proximal GI tract, colonic mucosa do not receive nutrition primarily from blood stream but from?
primary energy source if short chain fatty acid butyrate
49
Primary energy source for colonic epithelium?
butyrate (SCFA)
50
Na and H2O absorption in colon, active or passive?
H2O--> passive | Na--> active
51
Mammal cells do not produce butyrate, how do colonic cells get it?
bacteria ferment ingested dietary fiber
52
Broad spectrum antibiotics destroy local colonic bacteria, thus fermentation of dietary fiber does not occur, thus we don't have energy for colonocytes to absord Na and water thus we get?
watery diarrhea
53
How do we define diarrhea?
>3 loose stools daily
54
How do we define constipation?
< 3 stools weekly
55
Most common bacterial species in the colon?
most common bacteria-> bacteroides (anaerobic) | aerobic--> e.coli
56
Bowel prep and pre-op antibiotics before colonic surgical manipulation?
commonly done in US (however, some think broad spectrum antibiotics can destroy the normal colonic bacteria, reduce butyrate, less energy for colonocytes, weaker anastomosis)
57
Absolute contraindications to bowel prep?
complete bowel obstruction | free perforation
58
Elective colo-rectal cases are classified as?
clean-contaminated
59
When an elective clean contaminated colo-rectal case is done we need post-op abx?
routine abx for a clean contaminated segmental resection does not reduce infectious complications promotes c. diff colitis
60
Typical abx used pre-operatively for elective colonic cases?
2, 3rd gen cephalosporins or fluroquinolone + flagyl or clinda
61
What is diverticular disease of colon?
abnormal sac or pouch protruding from colonic wall | colonic diverticula are pseudodiverticula (protrusions of mucosa thru the muscularis layers)
62
Why are colonic divericula pseudodiverticula and not true?
true diverticulum--> all layers of colon protrude thru pseudo--> they don't protrusion of normal muscular layers
63
Age distribution of diverticula?
rare before age 30 2/3 of Americans will have diverticula by age 80
64
Dietary factors contributing to diverticulosis?
low fiber diet | diet high in carbs and meats
65
What causes diverticula to form in the colon?
herniations of mucosa thru the colon at sites of penetration of the muscular wall by arterioles
66
Why do we commonly see bleeding with diverticulosis?
usually diverticula are protrusion of mucosa thru the colonic wall at sites where the arterioles penetrate the muscular wall sometimes the arterioles are involved in the protrusion and form the dome of the diverticula
67
Why are colonic diverticula called false diverticula?
they only contain protrusions of mucosa
68
Where do diverticula form on the colon?
they form on the mesenteric sides Do not form on the anti-mesenteric sides
69
Diverticula affect what part of colon mostly?
sigmoid colon 50% descending colon 40%
70
Why is sigmoid common site for diverticula?
has smallest colonic diameter decrease in fiber, requires increased pressures to propel feces forward narrow sigmoid can generate pressures as high as 90 mmHg to propel feces forward--> diverticula
71
What causes diverticulitis?
perforation of a colonic diverticula
72
This is an extraluminal pericolic infection caused by extravasation of feces thru a perforated diverticulum:
diverticulitis
73
Symptoms of diverticulitis?
``` LLQ pain alterations in bowel habits fever/chills urinary urgency no rectal bleeding ```
74
Preferred imaging modality to reveal diverticulitis?
CT
75
What is the Hinchey classification of diverticulitis?
I--> pericolic or mesenteric abscess II--> walled-off pelvic abscess III--> generalized purulent peritonitis IV--> generalized fecal peritonitis
76
Analgesics to use and to avoid in diverticulitis?
AVOID--> morphine (increases intraluminal pressure) | USE---> meperidine (decreases luminal pressure)
77
After an uncomplicated bout of diverticulitis has resolved, what do we recommend next?
colonoscopy to check for cancer 6 weeks after
78
After a first attack of uncomplicated diverticulitis, resolved with antibiotics, what are the chances of a second attack?
25%
79
Do we offer younger pts surgery after first bout of diverticulitis?
50 pts younger than 40 were followed for 9 yrs post-1st attack, 2/3 did not require surgery these numbers are similar for diverticulitis in pts >50
80
Diverticulitis in immunocompromised pts?
selective sigmoidectomy after a single attack should be considered have diminished ability to combat an infection
81
How do we manage complicated diverticulitis with an abscess?
if abscess >2 cm, it needs to be drained percutaneously
82
When complicated diverticulitis with abscess have resolved after IV abx and percutaneous drainage, when do we perform surgery (sigmoidectomy)
electively in 6 weeks
83
Major cause of recurrent diverticulitis after sigmoidectomy is?
failure to remove entirely abnormal thickened bowel | recurrence rate is 12 % if distal sigmoid not resected
84
What's a common complication of diverticulitis?
fistula formation after percutaneous drainage from colon to skin colon to bladder, vagina, small bowel
85
How do we treat fistulas as a result of diverticulitis?
need to removed diseases sigmoid segment | diverticulitis forms more fistulas between colon and bladder than Crohn's dx or cancer
86
Why are sigmoid-bladder fistulas from diverticulitis more common in men?
uterus prevents close adherence of sigmoid to bladder in females (usually women with fistulas have had a prior hysterectomy)
87
Sxs of sigmoid-vesicular fistula?
pneumaturia fecaluria recurrent UTIs
88
Most reliable test to confirm colo-vesicular fistula in diverticulitis?
CT
89
If someone has a colo-vesicular fistula what do we do?
Abx first C-scope to exclude sigmoid cancer as cause of fistula (which requires extensive removal of involved organs vs diverticulitis as cause which requires segmental sigmoid resection and repair of bladder)
90
Surgical treatment of colo-vesicular fistulas?
fistula removal sigmoid resection anastomosis of distal descending colon to rectum usually bladder hole is so small, doesnt require repair leave Foley for 1 week or suprapubic catheter (larger holes repaired with absorbable chromic)
91
What causes generalized peritonitis from diverticulitis?
diverticulum perforates in peritoneal cavity, not sealed by body's defenses an abscess that was local, suddenly expands, bursts into peritoneal cavity
92
What is the most common surgical technique for control of infection in someone with generalized peritonitis from diverticulitis?
Hartmann's; rectosigmoid resection, end descending colostomy, closure of rectal stump
93
When do we restore intestinal continuity after someone has had a Hartmann's for perforated diverticulitis?
at least 10 weeks
94
What are two ways that diverticulitis can cause obstruction symptoms?
rare--> narrowing of sigmoid because of mucosal hypertrophy of bowel wall (poses diagnostic dilemma, difficult to distinguish if sigmoid cancer) likely--> SBO related to inflammatory and infectious aspects of diverticulitis (SB adheres to phlegmon or abscess) (Tx--> NG tube, antibiotics, drainage to treat infection)
95
What is DAC?
diverticular-associated-colitis rare subset of pts can have symptoms and pathology of diverticulitis that mimics Crohn's/UC
96
When colon gets twisted around its mesenteric axis, its termed?
volvulus leads to partial vs complete obstruction compromise of arterial supply imminent
97
Colonic volvlus causes what % of large bowel obstructions?
4%
98
Common locations of colonic volvulus?
sigmoid colon primarily cecal volvulus next
99
Most common location of colonic volvulvus?
sigmoid volvulus accounts for 2/3 of all cases
100
Common age distribution for sigmoid volvuvlus?
present near 7th-8th decade
101
Factors contributing to sigmoid volvulus?
``` older age constipation institutionalized pts (psychotropic meds affecting motility) ```
102
What do we see on abdominal xray of suspected sigmoid volvulus?
bent-inner tube sign, apex in RUQ
103
What do we see on CT scan of someone suspected of having sigmoid volvulus?
whorl sign
104
Contrast enema typically reveals point of obstruction in sigmoid volvlusus with what sign?
bird beak tapering sign
105
Non-operative tx of sigmoid volvulus?
rectal tube to decompress pt ( keep tube for 1-2 days)
106
Tx for sigmoid volvulus if unsuccessful decompression with rectal tube?
Hartmann's
107
Why is surgical intervention usually necessary in pts with sigmoid volvulus?
even if they get detorsed with rectal tube, recurrence rate is 70%
108
What's recurrence rate of sigmoid volvulus after successful detorsion with rectal tube?
70%
109
What's a cecal bascule?
"cecal volvulus" although true cecal volvulus almost never occurs cecum folds over anteriorly on stable ascending colon
110
Incidence rate of cecal vovulus?
<2 % of all adult intestinal obstruction | 25% of all cases of colonic volvulus in US
111
Age group affected by cecal vovluvlus?
pts in later 50s | sigmoid volvulvus is pts in 70-80s
112
Why is cecal volvulus possible?
cecum not tethered to retroperitoneum
113
What do we see on xray with suspected cecal volvulus?
dilated cecum, usually displaced to LUQ
114
Tx for cecal volvulus?
surgery
115
What is the surgical procedure of choice for cecal volvulus?
right hemi-colectomy with primary anastomosis, unless ischemia or gangrene present, then ileostomy needed
116
What's mechanical large bowel obstruction?
either luminal, mural, or extra-mural obstruction we see increase in intestinal contractility to relieve the obstruction
117
Most common cause of colonic obstruction in US vs Europe?
US--> CA | Europe--> colonic volvulus
118
Other causes of colonic obstruction?
luminal obstruction--> fecal impaction, inspissated barium, foreign body mural--> cancer, inflammatory processes extramural--> adhesions, hernias, tumors in nearby organs, abscess, volvulus
119
Sxs of large bowel obstruction?
failure to pass stool and flatus | increasing abd distention, crampy pain
120
What makes up colonic gas?
2/3 swallowed air | 1/3 fermentation bacterial products
121
What's a closed loop obstruction?
distal and proximal ends occluded | seen in volvulus, strangulated hernias, or when cancer occludes colonic lumen in setting on competent ileo-cecal valve
122
If colonic obstruction is due to cancer in mid to distal rectum, what do we do?
diverting colostomy to relieve the obstruction neoadjuvant chemo after with plan to resect primary tumor at later time
123
IF colonic obstruction is due to cancer in sigmoid colon, how do we proceed?
Hartmanns vs sigmoidectomy with primary colo-rectal anastomosis vs abdominal colectomy with ileo-rectal anastomosis
124
This is colonic distention, with signs and symptoms of colonic obstruction, in the abscence of an actual physical obstruction.
colonic pseudo-obstruction (Oglvie's syndrome)
125
Primary vs secondary pseudo-obstruction?
1---> motility disorder that is a familial visceral myopathy 2--> more common, assc with neuroleptic meds, opiates, parkinsons, lupus, hyperparathyroidism
126
Cause of colonic pseudo-obstruction?
hypothesis---> SNS overactivity over PSNS Tx-->> neostigmine (PSN mimetic)
127
You suspect colonic-pseudo obstruction, what test do we perform to differentiate between mechanical obstruction?
water-soluble contrast enema
128
Preferred initial test for colonic pseudo-obstruction?
water-soluble contrast enema
129
Colonoscopic use in Ogilvie's?
can be diagnostic and therapeutic run risk of over-distending the colon
130
Initial treatment of Oglivie's?
NGT decompression electrolyte correction IV fluids
131
When using neostigmine to treat Ogilivies what do we need to make sure?
make sure pt does not have a mechanical obstruction neostigmine stimulates colonic motility and increased intraluminal pressures in face of mechanical obstruction can cause perforation of bowel
132
Dosage of neostigmine for Ogilvies?
2.5 mg IV over 3 minutes (pts have sx resolution within 10 mins) success rate of decompression 90% after single use
133
SE of neostigmine?
bradycardia (pt needs to be in monitored setting) Tx--> atropine (unless significant cardiac dx or asthma)
134
Surgical tx of Ogilvie's syndrome?
if neostigmine, colonic decompression, or epidural anesthesia don't work, pt needs ex-lap loop colostomy usually vents prox and distal colon (if no signs of ischemia or perforation)
135
Commonly what age affected by ulcerative colitis?
pts < 30 yrs age second peak around 60 yrs age
136
This confers a protective effect on ulcerative colitis;
smoking | nicotine has been shown to induce remission in some cases
137
Smoking effect of UC vs Crohns dx;
UC--> protective Crohn's dx--> aggravating
138
This is a significant risk factor in UC:
+ family hx high degree of concordance with monozygotic twins
139
What genes are associated with UC?
HLA DR2
140
The major pathologic process of UC involves what layers of colon?
involves the mucosa + submucosa (usually mucosa is not ulcerated, it's more hyperemic) muscularis is spared
141
Hallmark of UC?
rectal involvement
142
What;s a diagnostic characteristic of UC? And how is this different from Crohn's?
continuous uninterrupted inflammation of the colonic mucosa, beginning in distal rectum and extending proximally Crohns--> normal areas of colon (skipped areas) can be interspersed between distinct segments of colonic inflammation
143
The entire colon, including cecum and appendix, may be involved in UC, but it does not involve what area that is commonly involved in Crohns;
terminal ileum
144
IS terminal ileum involved in UC?
no, terminal ileum involvement is seen in Crohns
145
Colonic strictures commonly seen in UC, usually in chronic UC at what %?
5-12 %
146
Crypt abscesses usually seen in UC, what are they?
neutrophils fill and expand the lumina of the crypts of Lieberkuhn (crypt abscesses can also be seen in Crohn's, infectious colitis)
147
Luminal involvement in UC vs Crohns?
UC--> mucosa + submucosa, spares muscularis Crohn's--> transluminal, involves all layers of intestinal wall
148
pANCA seen in what % of pts with ulcerative colitis?
86%
149
Do we see perineal disease with UC?
naa
150
Rectal vs anal involvement in UC?
rectal involvement 100% anal involvement is rare
151
Rectal vs anal involvement in UC vs Crohns?
UC--> rectal involvement 100%, anal is rare Crohns--> rectum is normal (rectal sparing), anal disease is common
152
What are the extra-intestinal manifestations of UC?
``` arthritis ankylosing spondylitis erythema nodosum pyoderma gangrenosum primary sclerosing cholangitis ```
153
This presents on tibia region as a reg plaque that progresses into an ulcerated painful wound;
pyoderma gangrenosum
154
What extra-intestinal manifestations of UC completely improve after colectomy?
arthritis ankylosing spondylitis erythema nodosum pyoderma gangrenosum
155
In pts with UC and primary sclerosing cholangitis, what are we concerned about?
risk of cancer is 5x greater than pts with UC alone
156
With colectomy for UC, what extra-intestinal manifestation does not resolve?
PSC
157
A pt with UC who presents with obstructive jaundice and abdominal pain, what do you suspect?
PSC
158
How do we diagnose UC?
endoscopically proctosigmoidoscopy is often sufficient in acute phase
159
What is the risk of developing cancer with UC?
``` cumulative risk increases with duration of the disease 25% @ 25 yrs 35% @ 30 yrs 45% @ 35 yrs 65% @ 40 yrs ```
160
Why do we assume colonic strictures in UC are cancerous until proven otherwise?
high risk of cancer with duration of UC
161
How do we screen surveillance pts with UC?
surveillance colonoscopy every 1-2 years, beginning 8 yrs after onset of pancolitis, or 12-15 yrs after onset of left sided colitis
162
For pts undergoing surveillance colonoscopies, traditionally 10 specimens were obtained, but that has changed to what?
at least 30 specimens need to be obtained
163
What do we do when we find high grade dysplasia on biopsy of colon of someone with UC?
proctocolectomy recommended
164
What are the three broad categories of drugs for treatment of UC?
aminosalycilates steroids immunomodulators
165
Most common therapy in tx of mild to moderate UC is?
aminosalycilates (sulfasalazine, mesalamine)
166
How do aminosalycilates like sulfasalazine work for UC?
block cyclooxygenase and lipoxygenase pathways of arachidonic acid and scavenge free radicals in colon mucosa
167
How do steroids work in UC?
effective in tx of active UC | block phospholipase A2, decreasing prostaglandins an leukotrienes
168
For UC disease limited to rectum and left colon, how can we use steroids effectively?
hydrocortisone enemas 2-3 x/daily are less absorbed thus have less side effects
169
These meds are often used for long-term management in pts with UC:
immunomodulators
170
What are the two immunomodulator drugs used in UC?
6-mercaptopurine | azathioprine
171
MOA of 6-MP and azathioprine in UC management?
induce DNA breaks | inhibit proliferation of rapidly dividing cells like T cells
172
What are the side effects of immunomodulators like 6-MP and azathioprine in UC management?
reversible bone marrow suppression pancreatitis
173
This immunomodulator drug has serious side effects:
cyclosporine; nepthrotoxic, hepatotoxic, seizures
174
This immunomodulator used in UC inhibits IL-2:
cyclosporine
175
This is a monoclonal antibody used in UC tx:
infliximab--> acts against TNF-a it can induce remission in a significant number of pts side effects--> infection susceptibility, lymphomas
176
What are the indications for surgery in UC?
fulminant colitis with toxic megacolon massive bleeding intractable dx dysplasia/carcinoma
177
Whats toxic megacolon?
life threatening condition seen in ptx with UC, Crohn's, pseudomembranous colitis bacteria infiltrate walls of colon, cause dilation--> imminent perforation
178
Surgical procedure for toxic megacolon?
proctectomy and anastomosis ill advised in acutely ill patient sx--> total abdominal colectomy, end ileostomy with rectal preservation (preserving the rectum allows for an ileo-rectal anastomosis down the road) usually rectum can be brought up as a mucus fistula or closed off
179
Tx for massive bleeding in UC?
massive bleed is rare | usually subtotal colectomy done
180
What's the most common indication for operative intervention in UC pts?
colitis with debilitating symptoms refractory to tx
181
Is segmental colectomy appropriate for UC?
no
182
Major disadvantage of proctocolectomy with end ileostomy for UC?
requires permanent ileostomy | done in older pts, those with poor sphincter fx, carcinoma in distal rectum
183
What is the most common operation for UC?
total proctocolectomy with IPAA (near total proctocolectomy with preservation of anal sphincter complex) ( a distal pouch of ileum is created from 30 cm of ileum and then stapled to the anus using a double-stapled technique)
184
In order to have a nice repair, the ileo-anal anastomosis needs to be tension free in total proctocolectomy with IPAA, how do we get more ileal length to bring down to anus?
mobilize posterior attachment of entire small bowel up to 3rd part of duodenum ileoc-colic artery can be resected close to SMA (gives another 2-5 cm) (SMA will feed the pouch after ileocolic resected) peritoneum of mesentery can be cut on anterior and posterior surface, relaxing incisions can give 1-2 more cm of length
185
Common complications of proctocolectomy with IPAA for UC?
SBO (27% of pts)--> tends to be severe, 50% of pts will need surgery pelvic sepsis from pouch anastomosis leaks--> usually diverting ileostomy & abscess drainage needed pouch-vaginal fistula in women pouchitis--> 7-30% of pts experience this
186
Most common procedure performed in emergent setting for UC ?
total abdominal colectomy with ileostomy (rectum is left in place for future continuity, and has a higher risk of bleeding and nerve injury during the emergent operation)
187
What is the ideal length of an ileal J pouch?
15-20 cm
188
Endoscopy in someone with severe-fulminant chronic UC would show what?
mucosal sloughing | deep ulcers with exposed musuclaris
189
Most common complication of ileal pouches?
obstruction | second most common is sepsis from leaks