Colorectal Surgery Flashcards
(43 cards)
Follow up scans for colorectal cancer
Normally 6 then 18minths with 6 monthly CEA levels for 3 years
Following chemo - 6month scan occurs at end of chemo
Following liver resection - 6 monthly for 2 yrs
Scoring system is for polyps
Haggis level determines the level of invasion within the polyp
Kikuchi level determine the degree of sun mucosal invasion in the colonic wall
Paris type - morphology of the polyp
Kudo groups - pit pattern
What is the most comman extracolonic manifestation of FAP
Adenoma toys duodenal polyps
Treatment of Anal SCC
Radial chemoradiotherapy
AIN 3 - risk of progression to invasive and 6 months follow ups required
AIN 1-2. Discharge
Is reoccurrence consider APER
Endoscopic changes in UC -early
Loss of the mucosal vascular pattern occurs as a result of mucosal oedema which obscures the underlying vessels. More advanced changes include; erythema, contact bleeding, ulceration and pseudopolyps
What percentage of FAP is not inherited
25%
Radiotherapy for rectal cancer
Rectal cancer if <15cm from distal margin to sphincters
Short course radio should be followed 4-8wrrks by surgery (chemo can extend time) - Stockholm 3 trial
For bulky nodes in mesotectum or the threatened CRM
Low pressure anal fissure
Medical tx
Advancement flaps
Uc vs campylobacter infection
The histological changes seen in both UC and Campylobacter infection are identical and therefore stool testing for this should be conducted in all cases of suspected UC
Pouchitits
Establish diagnosis with endoscopy and symptoms
Initial tx is metronidazole for 2/52 or cipro
If relapses quickly or 3 relapses in a year consider long term cipro or VSL 3 (probiotic)
5 yr survival rate for salvage APER for anal SCC
40%
Up to 75% for non salvage patients (respond to chemo rad)
Amount of serosa that can have mesentry removed on ilesotomy
5cm before risk of necrosis
Anal fissure
Medical treatment has not been shown to be superior to surgery (lateral internal sphincterotomy)
Sensitivity for Ct colonoscopy
93% sensitive and 97% specific
Types of fistula in abo
Intersphincteric (70%)
Trans-sphincteric (25%)
Suprasphincteric (4%)
Extrasphincteric (1%)
CMV histology
Intra cytoplasmic inclusions
Hematoxylin and eosin stains may reveal classic findings, which include giant cells with cytomegaly and large ovoid or pleomorphic nuclei containing basophilic inclusions (owl’s eyes, halo rim).
Histology in UC
Alteration of crypt architecture. Branching crypts with marked deviation of the crypt axis from the perpendicular; variation in crypt size and/or shape; shortened crypts, with bases of crypts elevated off the muscularis mucosae
Dense neutrophilic infiltrates and neutrophils in crypts (crypt abscesses)
Ulceration may be identified, although fissuring is often absent
Histology in Crohn’s disease
Areas of chronic inflammation, comprising increased lamina propria plasma cells and lymphocytes, in association with chronic architectural distortion with patchy, mild to severe, neutrophilic inflammation, including neutrophilic cryptitis, crypt abscesses, or erosions/ulcers
Skip lesions
Granulomas
Sub mucosal fibrosis
Fissuring
Radiation enteritis
Disordered crypts
Endarteritis obliterans
Fibrosis of the lamina propria
Ulceration and fistulation
Infective colitis
Increased cellularity in the lamina propria
Neutrophilic infiltrates
Loss of crypts
Collagenous collitis
Normal crypts with lymphocytic infiltrates and collagen deposition in the lamina propria
Solitary rectal ulcer histology
Fibromuscular obliteration
Surface ulceration
Little inflammatory activity
Earliest complication of ilesotmy
Necrosis
Fistula in a 6month year old
Low fistulae in ano are not uncommon in the first year of life. There is seldom any significant associated pathology, especially if the child is otherwise well. They seldom involve the sphincter and are best laid open, which children seem to tolerate well. Detailed imaging (which in this age group requires anaesthesia) is not appropriate at this stage.