com4 med bio Flashcards
(16 cards)
multifactorial traits
influenced by environment
monogenic trait
mendelian inheritance
polygenic trait
nonmendelian inheritance
nonmendelian inheritance causes 3 types of diseases
- multifactorial diseases
- diseases related to somatic cells
- mitochondrial diseases
discontinuous variation
mendelian inheritance
continuous variation
nonmendelian inheritance
discontinuous variation
- controlled by single gene / small number of genes
- qualitative characteristics
- major genes
- little effect of environment
continuous variation
- quantitative characteristics (measurable)
- multiple genes
- significant effect of environment
- polygenic traits
- bell shaped (gauss) curve
- minor genes
multifactorial traits
- environmental factors
- polygenic traits
polygenic traits
- multiple genes controlling phenotype
- no dominant or recessive
- bell-shaped curve
- difference b/w phenotypes decrease as # of phenotypes increase
examples for polygenic traits
- height
- weight
- heart rate
regression to the mean
in a polygenic system, parents with extreme differences in phenotype, tend to have offspring exhibiting a phenotype average of 2 parental phenotypes
empiris risk
risk of recurrence of a trait/illness based on known incidence in a particular individual
incidence
of new cases of a partşcular disorder diagnosed per year
prevalence
of individuals in a population who have a particular disorder at a specific time
concordance
agreement b/w traits exhibited by both twins
- twins show concordance if both have the trait
- twins are discordant if only 1 twin has the trait