com4 med bio Flashcards

(16 cards)

1
Q

multifactorial traits

A

influenced by environment

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2
Q

monogenic trait

A

mendelian inheritance

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3
Q

polygenic trait

A

nonmendelian inheritance

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4
Q

nonmendelian inheritance causes 3 types of diseases

A
  • multifactorial diseases
  • diseases related to somatic cells
  • mitochondrial diseases
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5
Q

discontinuous variation

A

mendelian inheritance

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6
Q

continuous variation

A

nonmendelian inheritance

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7
Q

discontinuous variation

A
  • controlled by single gene / small number of genes
  • qualitative characteristics
  • major genes
  • little effect of environment
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8
Q

continuous variation

A
  • quantitative characteristics (measurable)
  • multiple genes
  • significant effect of environment
  • polygenic traits
  • bell shaped (gauss) curve
  • minor genes
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9
Q

multifactorial traits

A
  • environmental factors

- polygenic traits

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10
Q

polygenic traits

A
  • multiple genes controlling phenotype
  • no dominant or recessive
  • bell-shaped curve
  • difference b/w phenotypes decrease as # of phenotypes increase
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11
Q

examples for polygenic traits

A
  • height
  • weight
  • heart rate
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12
Q

regression to the mean

A

in a polygenic system, parents with extreme differences in phenotype, tend to have offspring exhibiting a phenotype average of 2 parental phenotypes

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13
Q

empiris risk

A

risk of recurrence of a trait/illness based on known incidence in a particular individual

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14
Q

incidence

A

of new cases of a partşcular disorder diagnosed per year

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15
Q

prevalence

A

of individuals in a population who have a particular disorder at a specific time

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16
Q

concordance

A

agreement b/w traits exhibited by both twins

  • twins show concordance if both have the trait
  • twins are discordant if only 1 twin has the trait