Common Medication Flashcards
What is a useful fact about Paracetamol?
150mg/kg can be toxic, but very narrow therapeutic index, so drops off quickly at 125/mg
What is a useful fact about Ibuprofen?
If taken with Aspirin will Inhibit the cardioprotectice effects
What is a useful fact about co-codamol?
Enzyme converts to Morphine, however people (usually white) don’t have as much of the enzyme so have less effects. Therefore combined with paracetamol for these people. The opposite may also occur, in which too much effects with a low dose
What is a useful fact about codeine?
Taking more over a certain threshold doesn’t increase positive effects, just side effects as limit of enzyme conversion rate.
What is a useful fact about tramadol?
Also acts to limit serotonin reuptake, so can cause Antidepressants withdrawal symptoms when stopped, aswell as not completely reversed by naloxone
What is a useful fact about patients morphine?
Although tolderance to nausea and vomiting will improve over days, the Constipation only worsens. Tolerance to analgesics effects takes weeks to months
What is diclofenac?
An NSAID, primarily used to inflammation in the context of arthritis
What is a useful fact about diclofenac?
Has a higher risk of Gastrointestinal side effects than other common NSAIDS, therefore prescribed with PPI
What is a useful fact about aspirin?
JRCALC contraindicates in children under 16, this is due to risk of reyes syndrome in children as children fighting a viral infection have an active immune system and liver, which is disrupted by the aspirin causing damage
What is naproxen?
An NSAID
What is a useful fact about naproxen?
Usually prescribed due to low cardiovascular risk, however if GI concern is high then ibuprofen preferred
What is Dihydrocodeine?
An opiod, which is stronger than codeine, however more potent
What is a useful fact about Dihydrocodeine?
Metabolised less by the enzyme to convert to morphine, therefore less variability in results
What is Oxycodone?
Strong opiod
What is a useful fact about oxycodone?
Highest bioavailability meaning 60-70% is absorbed by bloodstream meaning higher and quicker risk of overdose
What is nefopam?
Non-opiod painkiller
What is gabapentin?
An Anticonvulsant which Decreases neuron excitability for Seizures and nerve pains
What is a useful fact about gabapentin?
Must be titrated slowly as it takes days to weeks to build up in the nervous system
What is Fentanyl used for?
X
What is a useful fact about fentanyl?
X
What is ketamine used for?
X
What is a useful fact about ketamine?
X
What is a useful fact about beta blockers?
Cardioselective beta blockers (prolol) reduce heart rate by 10-20, whilst non cardioselective (nolol, dolol) can decrease by 20-30
What is digoxin?
Increases strength of the hearts contractions for use mainly in congestive heart failure