Common Presentations and Differentials Flashcards

(36 cards)

1
Q

What are the differentials in a failure to thrive history?

A
Pyloric Stenosis
Coeliac Disease
IBD
Eating Disorder
GORD
Cystic Fibrosis
Cows milk protein allergy
Lactose Intolerance
Neglect
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2
Q

What systems reviews do you ask in a failure to thrive history?

A

General

GI

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3
Q

What are the key questions to ask in a failure to thrive history?

A
Detailed dietary and feeding history.
Hunger?
Activity levels, energy levels and amount of exercise? Any questions regarding eating disorders?
Number of wet/dirty nappies or times goes to the toilet? GI symptoms?
ASK TO SEE GROWTH CHARTS
PMH
Happy?
Behaviour?
Parent's weight and health
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4
Q

What are the differentials in a weight gain history?

A
Obesity
Familial Obesity
Cushing's Syndrome
Hypothyroidism
PCOS
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5
Q

What are the differentials in a childhood bruising history?

A
NAI
AI
ITP
HSP
Meningococcal Septicaemia
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6
Q

What are the differentials in a global developmental delay history?

A
Neglect/abuse
Chromosomal abnormality
Maternal use of drugs in utero
TORCH infection in utero
Prematurity
Hypoxic Brain injury
Hypoglycaemia
Intraventricular haemorrhage
Meningitis/Encephalitis
Head injury or hypoxic episode
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7
Q

What are the differentials in a delayed walking history?

A

Duchenne’s Muscular Dystrophy
Cerebral Palsy
Developmental Dysplasia of the Hip

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8
Q

What are the differentials in a delayed speech history?

A

Deafness
Neglect/abuse
Cleft palate
Familial

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9
Q

What are the differentials in a early puberty history?

A
Adrenal tumour/hyperplasia
Ovarian/testicular tumour
Familial
Intracranial tumour
CNS problem e.g. hydrocephalus
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10
Q

What are the differentials in a delayed puberty history?

A
Constitutional
Hypothyroidism
Systemic disease
Turner's - 45 XO
Klinefelter's - 47 XXY
PCOS
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11
Q

What are the differentials in a fits/faints history?

A
NEAD
Epilepsy
Breath holding 
Reflex Anoxic Syndrome
Febrile Convulsions
Vasovagal
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12
Q

What are the main causes of tachycardia in children?

A
Upset
Stranger fear
Pyrexia
Pain
SVT (>220)
Increased work (similar to exercise. I.e. using accessory muscles to breathe)
Cardiac failure
Hyperthyroid
Shock secondary to sepsis
Shock secondary to injury (accidental or non accidental)
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13
Q

What are the main causes of tachypnoea in children?

A

Congenital abnormality i.e diaphragmatic hernia
Shock secondary to injury, third space losses or sepsis
Primary respiratory illness i.e. Bronchiolitis
DKA
Cardiac Failure
Compensation for a metabolic problem

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14
Q

What could be the cause of a neonate who is more sleepy than usual?

A

Hypoglycaemia
Exhausted (due to work of breathing)
Encephalopathy secondary to infection
Hypoxia
Neurological problem following head injury
Encephalopathy secondary to a metabolic condition i.e. high ammonia

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15
Q

What are the key things looked at in the traffic light system for recognising the seriously unwell child?

A

Colour
Activity
Respiratory - rate, signs of distress, sounds, sats
Circulation and hydration - CRT, HR, hydration status, feeding, urine output
Temperature
Presence of rash
Focal neurological signs

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16
Q

What are the signs of dehydration in a child?

A
Dry mucus membranes
Sunken fontanelle
Reduced skin turgor
Reduced urine output
Reduced activity level - more sleepy than usual
Tachypnoea
Tachycardia
Reduced CRT
Eyes sunken and tearless
Hypotension
17
Q

What is the clinical triad for meningitis?

A

Neck pain/stiffness and other meningeal signs (photophobia, Kernig’s sign)
Fever
Headache

18
Q

What is the main difference between meningitis and meningococcal septicaemia?

A

Meningitis - presence of menigeal signs such as photophobia, neck stiffness, high pitched cry and positive Kernig’s and Brudzinski’s signs.
Meningococcal septicaemia - signs of systemic disease, inc. shock - cool peripheries, tachycardia, hypotension, prolonged CRT, altered mental state, leg pain, poor urine output.

19
Q

What is the first line treatment for someone with suspected meningitis or meningococcal disease in a child?

A

Emergency transfer to hospital

Parenteral Benzylpenicillin

20
Q

In secondary care, what treatment should be given to someone with a non blanching rash and signs of meningitis or meningococcal disease?

A

IV ceftriaxone

21
Q

Contraindications to performing an LP?

A
Shock
Raised ICP
Convulsions
Spreading or extensive purpura
Coagulation abnormalities
Superficial infection at LP site
Respiratory insufficiency
22
Q

Choice of treatment of a neonate (<3 months) with bacterial meningitis?

A

Cefotaxime with Amoxicillin

23
Q

What is the most common cause of viral meningitis in immunocompetent adults?

A

Enteroviruses

Others -
HSV
VZV

24
Q

What is the cause of bronchiolitis and what age does it occur?

25
What is the cause of croup and what age does it occur?
Parainfluenza virus | 6 months - 6 years
26
What are the causes of viral pneumonia?
RSV Parainfluenza Adenovirus Rhinovirus
27
What is the stepwise management of asthma and when can it be diagnosed?
>4 years | SABA - ICS - LABA - LRA - Increase ICS - Oral Steroids
28
What are the classic features of autism?
Impairment in social relationships Impairment in social communication Impairment in imaginative thought
29
Key features of ADHD?
Inattention Impulsivity Hyperactivity
30
What can cause a metabolic acidosis and high ammonia?
Cardiac failure Inborn error of metabolism Sepsis Liver failure
31
What are the main groups of inborn errors of metabolism that cause a hyperammonaemia?
Urea cycle disorders - ammonia typically >1000 with a resp alkalosis on ABG Organic Acidaemias - mixed picture, with lower ammonia than in urea cycle disorders, raised anion gap - remember these are not tested for on the Blood Spot test
32
What is the anion gap calculation?
(Na + K) - (Bi + Cl)
33
What is the peak age of presentation of intussusception?
3 months - 2 years
34
What is the most common cause of acute renal failure in children?
Haemolytic Uraemic Syndrome secondary to E.coli infection
35
What is the peak age of presentation for pyloric stenosis?
2-6 weeks of age
36
What is the most common cause of food poisoning in the UK?
Campylobacter