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Flashcards in complicated infections Deck (8)
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1
Q

name cephalosporins and carbapenems

A

cefalexin
cefotaxime
meropenem
ertapenem

2
Q

cephalosporins and carbapenems interactions

A

2nd and 3rd line for UTI and resp infections

- parenteral for severe/ complicated/ antibiotic resistant

3
Q

spectrum of cephalosporin and carbapenems

A
  • broad

- 3rd gen ceph better for pseudomonas

4
Q

MOA cephalosporins and carbapenems

A
  • bactericidal due to beta lactam ring. inhibition of cross linking of cell wall - lysis and death
5
Q

SE cephalosporins and carbapenems

A
  • GI upset
  • C diss
  • hypersensitivity esp if already to pens - cross reactive
  • neuro toxicity inc seziures esp if carbapeneems at high dose or to renal impairment patients
6
Q

CI to cephs and carba

A
  • anaphylaxis
  • allergy to pen or themselbes

relative

  • risk of C diff
  • renal impaired
  • epilepsy
7
Q

interactions of cephs and carbs

A
  • enhance effect of warfaring by killing gut flora making vit k.
  • increase nephrotoxicity of aminoglycosides
  • carbs - reduce efficacy and conc of valproate
8
Q

how can you administer carbs

A
  • IV only inject/infuse