Comprehension - L01-L02 Flashcards

1
Q

What are the 4 principles of Cell Theory?

A
  1. All organisms are composed of one or more cells
  2. The cell is the structural unit of life
  3. Cells can only arise by division from a pre -existing cell
  4. Cells contain genetic information passed from parent to daughter cell
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2
Q

What are some key features of Eukaryotic cells that are NOT in Prokaryotes?

A

Nucleus and Cytoplasm
Membrane bound organelles
Cytoskeletal system
RER
Golgi
Mitochondrion
Chromosomes

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3
Q

What is a covalent bond?

A

A chemical bond in which electron pairs are shared between two atoms

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4
Q

What are polar molecules and are they hydrophobic or hydrophilic?

A

Molecules with an uneven distribution of charge because the component atoms have different electronegativites
(Hydrophilic)

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5
Q

What are non-polar molecules and are they hydrophobic or hydrophilic?

A

Covalent bonds have a nearly symmetrical distribution of charge because the component atoms have approx the same electronegativities. (Hydrophobic)

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6
Q

What are the 6 polar uncharged amino acids?

A

So Three Girls Ate Toy Cats
Serine
Threonine
Glutamine
Asperagine
Tyrosine
Cysteine

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7
Q

What are the 5 Polar Charged Amino Acids?

A

AArdvark Grace-Anne Loses Argentinian Hennessy
Aspartic Acid
Glutamic Acid
Lysine
Arginine
Histidine

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8
Q

What are the 8 Non Polar Amino Acids?

A

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Alanine
Valine
Leucine
Isoleucine
Methionine
Phenylalanine
Tryptophan
Proline

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9
Q

What is the single amino acid that can fit in either hydrophobic or hydrophilic environments?

A

Glycine

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10
Q

What is a non-covalent bond?

A

A relatively weak chemical bond based on attractive forces between oppositely charged regions

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11
Q

What is an ionic bond?

A

Electrostatic interaction that occurs between groups of opposite charges

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12
Q

What is a hydrogen bond?

A

Electrostatic interaction between hydrogen atom (which is covalently bound to a more electronegative atom) and a second electronegative atom

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13
Q

What are Van Der Waals interactions?

A

A weak attractive force due to transient asymmetries of charge within adjacent atoms or molecules

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14
Q

What is the hydrophobic effect?

A

The tendency of non polar molecules to aggregate in order to minimize their collective interaction with surrounding polar water molecules.

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15
Q

The cell membrane contains a bilayer of what?

A

Polar phosphates
Nonpolar fatty acid tails

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16
Q

What are the characteristics of saturated fatty acids?

A

They lack double bonds

17
Q

What are the characteristics of unsaturated fatty acids?

A

One or more double bonds
Introduce a bend in the fatty acid
Natural occurring fatty acids have cis double bonds (bend)

18
Q

Are phosphoglycerides also phospholipids?

A

Yes

19
Q

All sphingolipids are phospholipids, T or F?

A

False. Only some sphingolipids are phospholipids

20
Q

What are the characteristics of phosphoglycerides?

A

Built on a glycerol backbone
Glycerol + 2 fatty acid chains + Phosphate group + Additional group

21
Q

In Phosphoglycerides, what are the charges of the following additional groups:
H (PA)
Choline (PC)
Serine (PS)
Ethanolamine (PE)
Inositol (PI)

A

H (PA): negative
Choline (PC): neutral
Serine (PS): negative
Ethanolamine (PE): neutral
Inositol (PI): negative

22
Q

What 3 things are considered membrane lipids?

A

Phosphoglycerides
Sphingolipids
Cholesterol

23
Q

What are sphingolipids built on?

A

Sphingosine

24
Q

What is an example of a sphingolipid?

A

Ceramide: sphingosine + Fatty acid

25
Q

What are the characteristics of a sphingolipid?

A

Amphipathic
Additional groups can be linked to head group
Longer and more highly saturated FAC than phosphoglycerides

26
Q

What is the role of a sphingolipid?

A

Signal transduction, membrane structure, and sensing

27
Q

If a carbohydrate is added to a sphingolipid, what is it called?

A

A glycolipid

28
Q

What is a cerebroside?

A

A simple sugar (like galactose) is added to a sphingolipid to form a glycolipid

29
Q

What is a ganglioside?

A

A cluster of sugars added to a sphingolipid to form a glycolipid

30
Q

What are the characteristics of cholesterol?

A

Amphipathic
Makes up 20-30% of the plasma membrane lipids in some animal cells
Impair movement of the FAT of the phospholipids

31
Q

What are the 4 general components of a phosphoglyceride?

A

Additional group
Phosphate
glycerol
2 FAT

32
Q

Phospholipid is a broad category that is composed of some (____) and all (___)

A

Phospholipid is a broad category that is composed of some sphingolipids and all phosphoglycerides

33
Q

What does membrane asymmetry affect?

A

Membrane permeability
Surface charge
membrane shape
stability

34
Q

What do membrane carbohydrates do?

A

Play important roles as receptors, sorting membrane proteins, and in cell recognition

35
Q

What are the 7 membrane functions?

A
  1. Compartmentalization
  2. Scaffold for biochem activities
  3. Selectively permeable barrier
  4. Solute transport
  5. Response to external stimuli
  6. Cell-cell communication
  7. Energy transduction