Comprehensive Final Exam Flashcards
(103 cards)
Which hormone begins follicle maturation?
- Follicular phase: days 1-14
- FSH causes maturation of the immature follicle
- There are also increased amounts of estrogen present
Which hormone is responsible for final maturation, and thus ovulation?
- LH is responsible for final maturation and ovulation
- Luteal phase: days 15-28, in a 28-day cycle
Estrogen
- hormones associated with “femaleness”
- Estrone, B-estradiol, estriol
- secreted by the ovaries, then placenta
- regenerates endometrial mucosa after menstruation
- inhibits FSH
- stimulates LH
- influences myometrium contractility, blood flow, and uterine mass
Progesterone
- secreted by corpus luteum, then placenta
- responsible for vaginal epithelium proliferation and thickening of cervical mucus
- hormone of pregnancy (relaces smooth muscle; maintains implantation; prevents rejection of the fetus)
Human Chorionic Gonadotropin (hCG)
- secreted by the trophoblast in early pregnancy
- stimulates progesterone and estrogen production by the corpus luteum to maintain the pregnancy until the placenta can take over
Human Placental Lactogen (hPL)
- also called human chorionic somatomammotropin
- produced by the syncytiotrophoblast
- An antagonist of insulin
- it increases the amount of circulating free fatty acids for maternal metabolic needs
- decreases maternal metabolism of glucose to favor fetal growth
Relaxin
- detectable in the serum of a pregnant woman by the time of the 1st missed period
- inhibits uterine activity
- diminishes strength of uterine contractions
- aids in the softening of the cervix
- has the long-term effect of remodeling collagen
- primary source is the corpus luteum, but small amounts are believed to be produced by the placenta and uterine decidua.
How long are ova and sperm viable/fertile?
Ova: fertile for 24 hours
Sperm: can survive for up to 72 hours; sperm can survive in the female reproductive tract for 48 to 72 hours, but are believed to be healthy and highly fertile for only about 24 hours.
Summarize the 3 shunts unique to fetal circulation
-Ductus venosus: fetal blood vessel that carries oxygenated blood between the umbilical vein and the inferior vena cava, bypassing the liver; it becomes a ligament after birth.
-Ductus arteriosus: a communication channel between the main pulmonary artery and the aorta of the fetus. It is obliterated after birth by rising PO2 and changes in intravascular pressure in the presence of normal pulmonary functioning. It normally becomes a ligament after birth but sometimes remains patent
Foramen ovale: special opening between the atria of the fetal heart. Normally, the opening closes shortly after birth; if it remains open, it can be repaired surgically.
Describe placental circulation
Maternal uteroplacental circulation:
-maternal BP via the endometrial arteries, spurts blood into the intervillous space
-maternal and fetal blood are very close facilitating gas exchange
-maternal blood bathes fetal chorionic villi
-maternal deoxygenated blood returns into maternal circulation via endometrial veins
Fetal placental circulation:
-fetal blood is well oxygenated from maternal “bathing” of O2
-it flows from the chorionic villi into the single large umbilical vein of the umbilical cord
-the umbilical cord vein takes the blood to the fetus
-the deoxygenated blood from the fetus is carried back to the placenta by 2 umbilical arteries
-these arteries divide into the arteriovenous system of the chorionic villi
-the maternal blood bathes the deoxygenated blood from the fetus and the process is started over
What is the venous structure of the umbilical cord?
2 arteries
1 vein
In the umbilical cord, what carries oxygenated blood and what carries deoxygenated blood?
Arteries carry deoxygenated blood
Vein carries oxygenated blood
What are some teratogens
Medication tobacco alcohol caffeine illicit drugs
When are teratogens most harmful and why?
Most harmful during the embryonic stage because “everything is forming.”
Subjective signs of pregnancy
- Presumptive
- amenorrhea, N/V, excessive fatigue, urinary frequency, changes in breasts, quickening (perception of fetal movement by mother)
Objective signs of pregnancy
- Probable
- changes in pelvic organs, enlargement of abdomen, Braxton Hicks contractions, changes in skin pigmentation, uterine soufflé, fetal outline, positive hCG
Diagnostic signs of pregnancy
- Positive
- Fetal HR, fetal movement, visualization of the fetus
What are expected maternal weight gains during pregnancy?
Underweight: BMI < 18; 24-80 lb gain
Normal weight: BMI 18.5-24.9; 25-35 lb gain
Overweight: BMI 25-29.9; 15-25 lb gain
Obese: BMI >30; 11-20 lb gain
Define gravida, para, and GTPAL
Gravida: number of pregnancies
Para: birth after 20 weeks gestation
GTPAL: Gravida, Term, Preterm, Abortion, Living
Gravida: number of pregnancies
Term: infants born 37-42 weeks
Preterm: infants born 20-36 weeks
Abortion: pregnancies ending in either spontaneous or therapeutic abortion
Living: number of living children
**Multiples: gravida/abortions refer to # of pregnancies and are counted as 1; term/preterm/living refers to the actual number of infants
What is GBS?
- Group B streptococcus
- found in the vagina or rectum of 10 to 30% of pregnant women
- GBS causes severe, invasive disease in infants
- Signs of illness include pneumonia, apnea, and shock
When is GBS test done?
35-37 weeks gestation
-rectal and vaginal swab of the mother
What does + GBS result mean?
- mother is positive
- given antibiotic prophylaxis at the onset of labor or the rupture of membranes
Describe the 5 variables of the biophysical profile (BPP)
- fetal breathing movements
- fetal movements of body/limbs
- fetal tone (extension/flexion of extremities)
- Amniotic fluid volume
- Reactive NST
How is each section of the BPP scored?
- Normal scored 2; abnormal scored as 0
- 8-10 reassuring (cannot be related to abnormal volumes of amniotic fluid)
- 6 equivocal; term-deliver; preterm-reassess in 24 hrs
- 4 or less; consider delivery