Comprehensive Final (Meds) Pharm Flashcards

(41 cards)

1
Q

Triptans: Sumatriptan (imitrex)

A

Adverse: dizziness, drowsiness, flushing, warm sensation, decreased carotid blood flow, serotonin syndrome; contraindicated for CVD, CAD, Stroke, HPTN, MI or Angina

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2
Q

Ergot Alkaloids

A

Promotes vasoconstriction- terminated ongoing migraines, numbness and tingling, myalgia, GI upset, and weakness in the legs

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3
Q

Lipid souble vitamins

A

K, A, D, E

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4
Q

Total enteral feeding care and maintenance: (9)

A

Check placment, ensure it does not dislodge, change tubing and bag, maintaining asepsis, maintain patency, monitor labs, start at 20-30ml/hr and gradually increase, check residual, 30 degrees HOB

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5
Q

Orlistat:

A

Fatty stools, flatus with discharge, fecal urgency and abdominal pain

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6
Q

Adverse effects for all antineoplastics:

A

Alopecia, mucositis (stomatitis), anorexia, n/v, diarrhea, neutropenia, anemia, thrombocytopenia, preg cat D or X, temporary or permanent infertility, fatigue

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7
Q

Alkylating Agents: Cyclophosphamide (cytoxan)

A

Hemorrhagic Cystitis, caustic to the tissue, maintain hydration to protect the bladder- COLD compress for IV site

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8
Q

Antimetabolites: Methotrexate

A

BB: Fatal- hemorrhagic enteritis, pneumonitis, SJS, folic acid anemia, caustic to the tissues, Use COLD for extravasation

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9
Q

Antitumor: Doxorubicin

A

Cardiotoxicity, severe vesicant, large bore IV, apply ICE

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10
Q

Vinka Alkaloid: Vincristine (oncovin)

A

Neurotoxicity: (numbness, tingling) constipation, severe vesicant, apply HEAT

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11
Q

Tamoxifen:

A

Uterine cancer, menopausal symptoms (vaginal dryness, moodiness, hot flashes), blood clots

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12
Q

Desmopressin

A

S/S of water intoxication, hptn, nausea, contraindicated w/ kidney disease and clotting patients

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13
Q

Levothyroxine (Synthroid)

A

Hyperthyroidism: tachycardia, anxiety, insomnia, wt. loss, anorexia, heat intolerance, diarrhea, menstrual irregularities, contraindicated with cardiovascular disease, monitor serum TSH 6 weeks after initiation and change of dose

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14
Q

Propylthiouracil

A

Hypothyroidism: bradycardia, wt. gain, fatigue, cold intolerance, hair loss; rash, and transient leukopenia- can cause severe liver toxicity

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15
Q

Bigs and Pitc

A

Increase in blood pressure, irritability, glucose, sodium
Decrease in Potassium, Immunity, Thyroxine, and calcium

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16
Q

Nursing implications for all antibiotics

A

Take the full medication to reduce resistance, take probiotics to prevent super infection, specificity- obtain a culture prior to starting antibiotic, monitor for allergies

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17
Q

Penicillins

A

Decreased effectiveness of oral contraceptives, do not give the same time as aminoglycosides, assess allergies

18
Q

Cephalosporin’s (Cefazolin)

A

Seizures (rare) nephrotoxicity, allergies to penicillins

19
Q

Tetracyclines: Sumycin

A

Photosensitivity, esophageal irritation, discoloration of the teeth, do not take with milk, or antacids

20
Q

Macrolides: erythromycin

A

Hearing loss, cardiotoxic effects, may increase effects of warfarin, Do NOT give with juices

21
Q

Aminoglycosides (gentamicin)

A

3 N’s: neurotoxicity (ototoxicity, loss of balance) nephrotoxicity, neuromuscular toxicity (severe muscle weakness, respiratory arrest), draw peaks and troughs

22
Q

Fluoroquinolones: Ciprofloxacin

A

Tendonitis, tendon rupture, extreme muscle weakness, phototoxicity, hepatoxicity

23
Q

Sulfonamides: Trimethoprim-Sulfamethoxazole

A

Crystalluria, oliguria, renal failure (increase fluid intake) , photosensitivity, hyperkalemia, allergies to sulfas

24
Q

Isoniazid:

A

Neuropathy, numbness, and tingling, take vitamin B6, take on an empty stomach, monitor liver enzymes

25
What happens to the immune cells in stage I of HIV
Decreased CD4+, increased CD8
26
What happens to the immune cells in stage II of HIV
CD4+ cells destroyed
27
Zidovudine:
weakness, anorexia, n/d, headache, CNS effects
28
Efavirenz:
CNS adverse effects, dizziness, sleep disorders
29
Lopinavir with Rotinavir (Kaletra)
Diarrhea, headache, and GI effects (n/v/d)
30
Interferron Alfa-2B
-Encephalopathy: Assess mental status -Assess for depression; homicidal/ suicidal ideation -Decreased immunity: assess WBC count, fever
31
Acyclovir
Take within 72 hours of symptoms, very important to stick with regimen, IV site can have some extravasation
32
Benzodiazepines( Lorazepam, ativan)
Long term memory loss, contraindicated w/glaucoma, liver disorders & addiction, - Antidote (flumazenil)
33
Non benzos & nonbarbituates (Ambien)
1. Fall asleep but not stay asleep 2. depression, suicidal ideation, hallucinations 3. Monitor respirations and CNS effects - Flumazenil
34
Serotonin syndrome
Abrupt/rapid, dilated pupils, termors, n/v/d, myoclonus, hyperreflexia
35
Nueromalignant syndrome
onset: days-weeks; led-pipe rigidity, Bradyreflexia
36
SSRI's (Zoloft/sertraline), escitalopram
Headache, nausea, CNS, weight gain, decreased libido, Monitor liver enzymes, do not take with St. Johns wort
37
Atypicals (bupropion)
Contraindicated in seizures pt's., dry mouth, insomnia, weight loss, seizures
38
Tricyclic antidepressants: (imipramine) (tofranil)
anticholinergic, photosensitivity, monitor cardiac Hx and cardiac enzymes
39
MAOI's (phenelzine/nardil)
Severe hypertension w/tyramine, orthostatic hypotension, Dry mouth, constipation, thacycardia
40
Lithium
Lithium toxicity (polyuria, tinnitus, involuntary movements, seizures, blurred vision, respiratory depression and hypotension); prevent dehydration, monitor CBC, blood electrolytes, renal function tests, thyroid
41
CNS Stimulant: Methylphenidate (Ritalin)
Come in every 1-3 months for eval; nervousness, insomnia, anorexia, monitor sleep disturbances and eating