Flashcards in Concepts in rheumatology Deck (14):
what are the two main categories of arthritis?
Non-inflammatory arthritis (commonly osteoarthritis)
What can inflammatory arthritis be further subdivided into?
Seropositive (autoantibodies in serum):
-Inflammatory bowel disease arthritis
What is the assoc condition with anti-CCP antibody?
What are the assoc condition with anti-nuclear antibody?
SLE, Sjogrens syndrome, Systemic sclerosis, MCTD, autoimmune liver disease`
What antibodies are found in SLE?
What are the antibodies found in sjogrens syndrome?
What antibody is found in limited systemic sclerosis?
What antibody is found in diffus systemic sclerosis?
What antibody is found in mixed connective tissue disease?
Anti-RNP antibody and ANA
What antibody is found in myositis?
What antibodies are found in anti-phospholipid syndrome?
What differentials are included with ANCA (anti-neutrophil cytoplasmic antibody)
small vessel vasculitis (GPA, EGPA, MPA)
What are the features of inflammatory conditions:
Joint pain – effect of activity
- Diurnal variation
Morning stiffness (>30mins)
Soft tissue swelling (synovitis)
May have other systems affected
May have inc. : PV/ESR/CRP
PV- plasma viscosity
ESR – erythrocyte sedimentation rate
CRP – c-reactive protein