Congenital defects Flashcards

(44 cards)

1
Q

What are the 3 most common congenital heart defects in dogs?

A

Patent ductus arteriosus
Subaortic stenosis
Pulmonic stenosis

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2
Q

What are the 2 most common congenital defects in cats?

A

Mitral dysplasia

Ventricular septal defect

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3
Q

What 5 things can you use to commonly help diagnose a congenital heart disorder?

A
Signalment/history/exam
Chest radiographs
ECG
Echocardiography
PCV/TPP
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4
Q

What 2 things will you find during a clinical exam in a dog with patent ductus arteriosus?

A

Machinery murmur in left heart base
-no silence
Hyperkinetic pulses
-diastolic pressure is low

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5
Q

Over time what will turbulence in an artery lead to?

A

Arterial dilatation

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6
Q

In PDA what direction is the blood usually shunted?

A

Left-to-right
From LV - lungs - LA - LV
-over circulation

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7
Q

What type of dog is PDA most common in?

A

Young small dogs

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8
Q

What things may you see on a radiograph for a dog with PDA?

A

Over-circulation of the lung fields
Dilated main pulmonary artery and descending aorta
Enlarged left atrium
Pulmonary oedema with congestive heart failure
3 ‘knuckles’ on VD - Aortic arch, pulmonic artery and oracle

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9
Q

How do you treat a left-to-right shunting PDA?

A

Surgery as early as possible

Treatment for congestive heart failure if needed

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10
Q

What surgical method is used to fix left-to-right shunting PDA?

A

Trans-arterial ductal occlusion with coils

-Coil with fluff on it promotes clotting, fibrosis and healing of area

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11
Q

What direction does the blood flow in a reversed PDA?

A

Right-to-left
RV-Body-RA-RV
-bypasses the lungs and left side of heart

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12
Q

How do you treat a dog with right-to-left shunting PDA?

A
Not surgery - has turned into a pressure release valve
Phlebotomy - blood letting
\+/- hyroxyurea to hit marrow 
Enforced rest
Avoidance of stress
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13
Q

What is the most common site for sub-aortic stenosis?

A

Sub-valvular 95%

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14
Q

What is the most common signalment for a dog with subaortic stenosis?

A

Large breed dog

-It is autosomal dominant with other genes influencing phenotype

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15
Q

What is the pathophysiology of subaortic stenosis?

A
Variable severity
Subvalvular fibrous ring
Develops within first months of life 
LV pressure overload
Concentric hypertrophy
Inadequate coronary perfusion
Worsening outflow tract obstruction
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16
Q

What are 4 history findings for a dog with subaortic stenosis?

A

Exercise intolerance
Syncope
Left-sided heart failure
Sudden death

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17
Q

What are 2 findings you can get from a clinical examination of a dog with subaortic stenosis?

A

Slow-rising hypokinetic pulses
Harsh systolic heart base murmur which radiates widely
+/- low heart base thrill
-can hear murmur all over body and can be very loud

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18
Q

Why is echocardiography important in a dog with subaortic stenosis?

A

To confirm diagnosis

Determine the severity of narrowing

19
Q

How do you treat a dog with subaortic stenosis?

A

Refer for surgery for balloon dilatation or open heart
Beta-1 blocker - Atenolol
Exercise restriction

20
Q

Why should you give a dog with subaortic stenosis beta-1 blockers?

A

To stop the heart working so hard and to prevent worsening

21
Q

Where does pulmonic stensosis usually occur?

22
Q

What type of animal does pulmonic stenosis most commonly occur in?

A

Small dogs
-Congenital defect
Rare in cats

23
Q

What are some history findings for a dog with pulmonic stenosis?

A

Asymptomatic usually until over 1y.o
Poor exercise tolerance
Syncope
Right-sided heart failure

24
Q

What are some clinical findings for a dog with pulmonic stenosis?

A
High left base systolic ejection murmur
\+/- thrill there
No radiation to carotids
\+/- jugular pulse
\+/- arrhythmias
25
In a dog with pulmonic stenosis, what are 2 findings for both radiographs and ECG?
Radiography -Right ventricular enlargement -Main pulmonary artery bulge on DV ECG -Exercise-precipitated ventricular tachyarrhythmias -Signs of right-sided cardiac enlargement
26
How do you treat a dog with pulmonic stenosis?
Like one with subaortic stenosis - ECG to confirm diagnosis and severity - Refer for balloon dilatation - Exercise restriction - +/- beta blocker - If needed treat for congestive heart failure
27
What is the blood flow in a ventricular septal defect?
LV-RV-Lungs-LA-LV - Bypasses systemic circulation - Volume overload in RHS
28
What will you hear on auscultation in a dog with a ventricular septal defect?
Harsh holosystolic murmur | Loudest on the right side
29
What will you find in radiography of a dog with a ventricular septal defect?
Left-sided enlargement Pulmonary over-circulation Variable right ventricular enlargement
30
What findings will you see in an ECG and echocardiography of a dog with ventricular septal defect?
Echo -Definitive diagnosis ECG -Left-sided enlargement
31
What are 3 possible outcomes from a ventricular septal defect?
May tolerate it May develop early pulmonary hypertension May develop left-sided congestive heart failure
32
What is the blood flow for an atrial septal defect?
LA-RA-RV-Lungs-LA Over-circulation Bypasses LV and systemic circulation
33
What will you find on auscultation in a patient with an atrial septal defect?
Fixed splitting of S2 -Prolonged RV emptying +/- systolic murmur over left heart base +/- diastolic murmur on the right side
34
What will you see on radiographs in a patient with an atrial septal defect?
Right-sided cardiac enlargement Dilatation of the main pulmonary artery Over-circulation of the pulmonary vessels
35
What 4 things make up a tetralogy of fallot?
``` Right ventricular outflow tract obstruction Secondary right ventricular hypertrophy Ventricular septal defect Overriding aorta (dextrapositioned) ```
36
In tetralogy of fallot what 2 changes are primary?
Right ventricular outflow tract obstruction | Ventricular septal defect
37
What can occur as a consequence of an overriding aorta in tetralogy of fallot?
Blood can go from the RHS to the LHS as it is very hypertrophied and strong -Cyanotic heart disease
38
Embryologically tetralogy of fallot is a consequnce of what?
Conotruncal septal malformation
39
What are some history and clinical findings of an animal with tetralogy of fallot?
``` Can be tolerated for years Exercise intolerance Cyanosis Usually murmumr from pulmonic stenosis is heart Erythrocytosis - elevated PCV ```
40
Why do you get an elevated PCV in heart conditions associated with cyanosis?
Because the chronic low oxygen levels cause an increase in erythropoietin and RBC production
41
What will you find on radiographs of a patient with tetralogy of fallot?
Normal sized, or slightly enlarged heart | Pulmonary Undercirculation
42
How do you treat a dog with tetralogy of fallot?
Phlebotomy if PCV over 65% +/- hyroxyurea to lower PCV Enforce rest Avoid stress
43
Why do you use hydroxyurea in cyanotic heart disease?
Cyanotic heart disease causes increased erythropoietin response and therefore elevated PCV Hydroxyurea works by limiting new RBC production
44
Why may you use phlebotomy and hydroxyurea together or in combination when treating cyanotic heart disease?
Phelbotomy causes an immediate reduction in PCV, but overtime the body will produce new RBC's to overcome this Hydroxyurea limits new RBC production and therefore takes 2-3 months to see effects, however these are more long-term medication