Congenital Heart Defects Flashcards

1
Q

What is the haemodynamic effect of a L-R shunt?

A

In terms of oxygenation, this is not a concern here. However there is increased blood flow around the pulmonary circulation which can lead to pulmonary hypertension and damage to the pulmonary vessels.

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2
Q

What is the problem with a R-L shunt?

A

This means that deoxygenated blood bypasses the lungs and enters the systemic circulation. This causes cyanosis.

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3
Q

What type of defects are aortic stenosis, pulmonary stenosis, coarctation of aorta and mitral stenosis all examples of?

A

Acyanotic defects. The blood is still sufficiently oxygenated.

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4
Q

Give some examples of cyanosis heart defects.

A

Tetralogy of Fallot, R to L shunts, transposition of great vessels, univentricular heart.

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5
Q

With which organ do we associate the cause of cyanosis to lie?

A

Heart. The lungs are very complex organs and so if oxygenation is insufficient then they can divert blood elsewhere.

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6
Q

What problems can be associated with Atrial Septal Defect?

A

This is where there is a hole in the interatrial wall. Blood is shunted L to R causing increased blood flow through R side of the heart. Pulmonary hypertension and R side heart failure can occur.

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7
Q

Where in the interventricular wall does ventricular septal defect most commonly occur?

A

It most commonly occurs in the membranous portion, however it can occur at any point in the septum.

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8
Q

What effect on the left ventricle does ventricular septal defect have?

A

This causes a L to R shunt meaning there is increased blood flow into the pulmonary circulation. This leads to LV overload due to the excess venous drainage.

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9
Q

What is the effect of Ventricular septal defect on the body?

A

As it is a L to R shunt there is a lower volume of blood pumped to the body so the heart has to pump harder to ensure that blood supply is sufficient.

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10
Q

What is the name for the condition where there is obstruction of blood flow into aorta during systole due to narrowing of the aortic valve?

A

Aortic stenosis

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11
Q

What is coarctation of aorta and what does it cause?

A

This is a narrowing of the aorta which commonly occurs after the left subclavian vein. This leads to high BP in the upper limbs and low BP in the lower limbs.

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12
Q

What is unusual about the congenital heart defect: tetralogy of Fallot?

A

The interplay of the four defects makes it compatible with life.

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13
Q

What defects comprise tetralogy of Fallot?

A

Pulmonary stenosis, VSD, right ventricular hypertrophy and overriding aorta.

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14
Q

What is the significance of pulmonary stenosis being a defect in tetralogy of Fallot?

A

It prevents high blood flow through the pulmonary circulation.

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15
Q

What is tricuspid atresia? What is required for there to be blood flow to the lungs?

A

This is where there is no blood flow from RA to RV. There is an entire R to L shunt of the venous return. For blood to get to lungs,beds a patent ductus arteriosus or a VSD.

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16
Q

In what condition is the left heart very underdeveloped? What is needed in order to sustain life?

A

Hypoplastic left heart. There must be a R to L shunt in order for this to be comparable with life as the right side of the heart support systemic circulation.

17
Q

What is necessary for transposition of great arteries to be viable with life?

A

L to R shunt. Either Atrial septal defect, Ventrical septal defect or patent ductus arteriosus.

18
Q

What is pulmonary atresia?

A

This is where there is no connection between RV and pulmonAry artery and so there is a R to L shunt of entire venous return. A patent ductus arteriosus is necessary for supporting life and blood flow to lungs

19
Q

What other defect is needed alongside univentricular heart for life to be sustained?

A

Transposition of the great vessels.

20
Q

Name three different factors which can cause congenital heart disease.

A

Infection of mother during pregnancy, environment and genetics