Connective Tissue Flashcards Preview

BIOL 302 > Connective Tissue > Flashcards

Flashcards in Connective Tissue Deck (53):
1

stroma

connective tissue that surrounds tissue component of organ

2

parenchyma

functioning part of organ

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functions of connective tissue

1. mechanical support and protection of soft tissue
2. physiological support (molecular exchange)
a. forms a pathway for blood vessels and nerves
b. fluids of connective tissues act as a medium of exchange for metabolites between tissues and blood vessels
3. storage of energy in the form of fat
4. defense against infection
5. repair of injuries
6. maintain boundaries
7. cell adhesion and movement

4

components

fibres, ground substance, cells

5

ground substance

aqueous, tends to be removed

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collagen properties

round and squiggly; inelastic; tensile strength; storage of strain energy; abundant

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elastic

thin; when pulled taut, have sharp angles; can also be squiggly

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collagen structure

molecule - glycine, proline, hydroxyproline triple helix
fibril - bundle of triple helices
fiber - bundles of fibrils
tissue - tendon, bundles of fibers

9

types of collagen (and class)

type 1 - fibrils, bones, tendons
type 2 - cartilage
type 3 - reticular fibers
type 4 - nonfibrillar (basement membrane)

10

elastic fibers properties

-strech
-flexibility
-branched
-fenestrated sheets

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ground substance component

-glycosaminoglycans (GAGs)
-proteoglycans

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ground substance function

-molecular highway/parking lot
-molecular exchange
-hydrating molecles
- more = looser
-nutrient delivery
-cell movement (plasma, mast cells)

13

cells found in connective tissue

-fibroblasts
-macrophages
-plasma cells
-mast cells
-leukocytes
-adipocytes

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fibroblast function

synthesize matrix
wound healing

15

fibroblast property

dense nuclei in connective tissue
large nucleus = active

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fibrocyte

thin dense nucleus

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macrophage

called monocyte in blood
v good at endocytosis (particle and dye)

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mast cell

primary immune response
histamine
large cells - red/purple granules

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plasma cell

b-lymphocyte in blood
make antibodies (sometimes see golgi bc they're working so hard)
large nucleus (clock face) --> heterochromatin

20

leukocytes

-neutrophil
-eosinophil
-lymphocyte

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adipocyte types

unilocular, multilocular

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unilocular

dynamic energy storage
white fat

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multilocular

brown fat - for hibernation - in bears and such
hella mitochondria

24

classifications of connective tissue

connective tissue proper, specialised connective tissue, and supporting connective tissue

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types of connective tissue proper

loose (areolar, mucous)
dense - regular (tendon, IEL) or irregular (everywhere)

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types of specialised connective tissue

identification (classification):
reticular (loose), adipose (loose), elastic, hematopoietic, blood

27

what are the supporting connective tissues?

cartilage
bone

28

loose connective tissue

more nuclei than fibres
pale, pinkish colour

29

areolar connective tissue

loose connective tissue
abundant but hard to see - fibres easily visible when ground substance removed
diverse cell population: fibroblasts, lymphocytes, leukocytes

30

mucous connective tissue

loose
spare cells (no leukocytes)
more ground substance than fibres
fibroblasts
collagen, no elastin
umbilical cord

31

reticular connective tissue - what type collagen? what class of connective tissue? characterise it. where is it found?

reticular fibres
type 3 collagen
specialised connective tissue
loose connective tissue
found in soft cellular tissues (lung/liver/lymphoid)

32

adipose connective tissue

each cell has single fat vacuole
white fat
energy storage

33

multilocular

each cell has many fat vacuoles
shivering
generate heat

34

dense irregular connective tissue

more fibres than ground substance
more fibres than nuclei
mostly collagen
disorganized appearance, no pattern
few cells - most are fibroblasts
dermis of skin
under most epi
resists stress in multiple directions

35

dense regular connective tissue

more fibres than ground substance (nuclei)
mostly collagen + elastin
organization repetitiveness
few cells - fibrocytes
tendons, ligaments
resists stress in 1 direction (fibres are oriented)

36

what are the cells in cartilage? what do they rest in?

chondrocytes; lacunae

37

what are the two matrices of cartilage? what relative colours do they each stain?

territorial - darker
interstitial - lighter

38

ground substance

no blood vessels or nerves
passive diffusion of nutrients limits size

39

fibers associated

collagen
elastin

40

hyaline cartilage

supportive, protective, growth - precursor of bone
spare cells
isogeneous groups are obvious
dense irregular connective tissue

41

characterize hyaline cartilage

dense irregular connective tissue

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identify a type of hyaline cartilage

perichondrium

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elastic cartilage

supportive
cells closely packed
isogeneous groups NOT obvious
dense irregular connective tissue

44

characterize elastic cartilage

dense irregular connective tissue

45

identify a type of elastic cartilage

perichondrium

46

perichondrium

consisting of elastic cartilage and hyaline

47

fibrocartilage

protective
sparse cells
isogeneous groups in ROWS
red nuclei
dense arrow of collagen fibers
ALWAYS blue stain w red nuclei

48

connective tissue diseases

sarcoma
Ehler's-Danlos
Stickler's syndrome
Marfans
scurvy

49

sarcoma

occurs in people w AIDS, but rare otherwise

50

Ehler's-Danlos

collagen mutation

51

stickler's syndrome

causes cleft palate mutation

52

marfan's

mutations in fibrillin

53

scurvy

issue w collagen formation bc of no vitamin C in the body
bleed to death