Connective Tissue and Vas. Flashcards
(22 cards)
What are the antibodies that will be seen in SLE?
dsDNA
Smith
ANA
C3, C4 will be decreased
What would you expect the UA of an SLE patient to look like?
protein and casts
How will the presence of lupus anticoagulant effect the aPTT
prolong it
This disorder has + anti-histone Abs
Lupus like, drug induced
What is a common clinical finding that is associated with neonatal lupus?
Complete heart block
Renal crisis is characterized by 3 things which are…
Malignant HTN
Hemolytic anemia
Progressive renal insufficiency
What antibody will be seen in Limited SCC
Anti-centromere
Anti-Scl70 and Anti-RNA are seen in which disorder?
Diffuse SCC
What is the major diagnostic test for sjogren syndrome?
Lip biopsy
Which diagnostic factors will be present in Sjogren syndrome?
Polyclonal hyperglobinemia
Anti SSA
Anti SSB
This disorder will have a +Anti-Jo1 and elevated CK and aldolase
Dermatomyositis
This disorder will have a +Anti-Jo1 and an elevated CK
polymyositis
This disorder will have Anti-cN1A autoantibodies and a mildly elevated CK
Inclusion body myositis
Anti-basement membrane Abs will be seen in….
Goodpasture syndrome
These disorders are ANCA positive
GPA (Wegeners)
Eopsinophilia Granulomatosis with polyangitis
This disorder has a triad associated with it which is,
Recurrent mouth ulcers
Genital ulcers
Eye inflammation
Bechet syndrome
______ is the presence of pustules at the site of sterile needle pricks
Pathergy; seen in Bechet
HLA-B51 is seen in??
Bechet syndrome
THE LUNGS ARE SPARED IN….
Polyarteritis nodosa
This is also knowns as the pulseless disease
Takayasu disease
This disorder will have an elevated ESR and CRP with clinical findings of a headache, jaw claudication, and visual abnormalities
Giant cell arteritis
Which labs will be elevated in polymyalgia rheumatica?
Elevated ESR and CRP
