contraindications Flashcards

1
Q

tolbutamide, chlorpropamide, tolazamide

glyburide, glipizide, glimepiride

A

sulfa allergy

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2
Q

hydrocortisone, cortisone, prednisone, prednisolone, dexamethasone, fluticasone

(corticosteroids)

A

NO CONTRAINDICATIONS in adrenal insufficiency

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3
Q

propylthiouracil

A

liver injury/ failure

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4
Q

exemestane

(aromatase inhibitor)

A

pregnancy- Cat X

premenopausal women

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5
Q

radioactive iodine

A

pregnancy

people who lack childcare

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6
Q

mifepristone

(antiprogestin)

A

pregnancy

breastfeeding

people taking glucocorticoids

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7
Q

“dronates”

bisphosphonates

A

ORAL contraindicated in:

pts w/ esophogeal dz

pts who can’t stay upright for an hour

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8
Q

“glutides”

+

exanetide

(GLP-1 agonists)

A

thyroid CA

hx of pancreatitis

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9
Q

mag sulfate

nifedipine

A

contraindicated to combo these (CV collapse)

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10
Q

metformin

A

lactic acidosis

kidney dz

liver dz

hypoxia (related- CHF, COPD)

alcoholism

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11
Q

leuprolide

goserelin

cetrorelix

ganirelix

A

sex steroid dependent CA

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12
Q

estradiol

estriol

estrone

A

thromboembolic disorders

smoking and over 35

breast CA (estrogen dependent neoplasms)

undiagnosed genital bleeding

liver dz

uncontrolled HTN

pregnancy

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13
Q

finasteride

dutasteride

(5 alpha reductase inhibitors)

A

teratogenic

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14
Q

“gliflozin”

SGLT-2 inhibitors

A

renal impairment

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15
Q

combo oral contraceptives

A

thromboembolic phenomena

estrogen dependent neoplasms

pregnant

smoking and over 35

caution w/: liver dz, DM, seizures

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16
Q

propranolol

A

asthma

DM

17
Q

ergonovine maleate

methylergonovine maleate

(ergots)

A

NEVER to induce labor

hepatic or renal dz

18
Q

“glitazones”

(thiazolidinediones)

A

CHF

liver dz

pregnancy cat C

19
Q

teriparatide

abaloparatide

rhPTH

A

osteosarcoma (Black Box)

caution w/ pts susceptible to osteosarcoma:

pagets

open epiphyses

radiation thx

20
Q

carboprost tromethamine

A

acute diseases:

cardiac

pulmonary

renal

hepatic

21
Q

“gliptins”

(DPP-4 inhibitors)

A

hx of pancreatitis