contrast and medicine in imaging Flashcards

(43 cards)

1
Q

what 3 reasons for using contrast

A
  • differentiate anatomy
  • differentiate patholofy
  • provides info on function
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are the 2 categories of contrast and give examples

A

positive (bright on CT) E.G iodinated/IV administrated

negative (dark on ct) e.g gas, water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

osomolality

high ormolu (ionic)
low osmolar (non ionic monomer)
iso osmolar (non ionic dimer)

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

3 main risks with contrast

A
  • extravasation (leaking out of vein)
  • allergic reaction
  • acute kidney injury
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the 3 types of fixed timings with contrast

A

arterial
portal venous
delayed phases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

gadolinium is used in MRI, this is toxic. why and how is it excreted from the bodu

A

toxic as it completes with Ca2+

  • cant be excreted so it binds to other molecules to be excreted
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

linear agents are restricted for usage due to what disorder it causes

A

nephrogenic systemic fibrosis (fibrosis of skin, joints etc)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is the mechanism of gadolinium and how does this affect the way it looks on images

A
  • shortens t1 decay (increase image brightness in t1w)
  • shortens t2 ( limited/no use in t2w)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

if theres too much gadolinium, what happens to signal

A

t2 properties overwhelm t1 properties and signal is lost

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

radiographer are part of PGD, what is this

A

patient group directive

  • legal framework allowing certain registered health professionals to supply or administer certain meds to a PRE DEFINED GROUP of patients without needed to see prescriber
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is PSD

A

patient specific directive

  • group prescription (symptoms within a scope can be given this drug)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what are the 2 main routes of drug prescribing

A

oral
IV (syring or pump)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what is an analgesia

A

analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what range of sedation can be given to patients (what is the most commonly used)

A

anxiolytic (reduced anxiety) to general aesthetic (not routine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what drug is commonly used as local anaesthesia

A

lidocaine

  • injected in skin surface deeper structures
  • often used for biopsy sites or dental anaesthesia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

lidocaine can also be used for what medical symptom, thus isnt injected via vessels

A

cardiac arrythmia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what can lidocaine be combined with to prolong action via vasocontriction

A

adrenaline/epinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

for CT guided biopsy:
- local anaesthetic in skin surface and deeper tissue
- sedation may be needed if hard procedure or patient extra anxious

  • systemic analgesia f painful after
19
Q

what are the opioids and non-opioids are given as a form of systemic analgesia (pain killer)

A

opioids : fentanyl

non-opioids: NSAIDS, paracetamol, entonox

20
Q

benzodiazepine is a class of medications that slow down activity in your brain and nervous system, which form of this is most commonly given in imaging

A

midazolam

(anxiolytic (anxiety relief) and amnesic properties)

21
Q

remember that sedatives such as midazolam cannot be given by radiographer, this must be prescribed by proper staff e.g doctor or sedation team

22
Q

what is 2 most common general anaesthetic prescribed

A

propofol (only administered by anaesthetic team)

ketamine (again only given by dedicated team or experienced individual)

23
Q

sodium pico sulphate is a chemical compenent given to clear bowls, what are the 3 types that can be given

A
  • picolax
  • citrafleet
  • citramag
24
Q

how do sodium picosulfate work and what do u use it for

A

stimulant laxative

  • clear faecal residue before colonic investigation
25
positive oral contrast is sometimes used in CT colonogrpahy to 'tag' faecal matter allowing it to be digitally subtracted
26
what 2 drugs is commonly used to decrease peristalsis for bowel imaging and what is average dose given
buscopan (antispasmodic) glucagon (anti-peristaltic) (more so in USA) - 20mg IV/IM dose
27
what are some side effects of buscopan
blurred vision constipation dry mouth palpitation urinary retention
28
give reasons why glucagon is not as good as buscopan
not as effective not as well tolerated more expensive
29
what drug is commonly used for bowel wall imaging
- MANNITOL (oral contrast in MRI/CT)
30
why is mannitol used
- distends small bowel allowing visualisation of wall - hyperosmolar so draws water into the bowel lumen
31
note that mannitol has similar imaging looks to water (neutral contrast agent in CT) mannitol can also be used to remove oedema
32
side effects of mannitol
diarrhoea bowel spasms flatulence
33
what are beta blockers used for and what drug is commonly used
reduce heart rate (negative chronotropic effect) / reduce heart contractibility (negative inotropic effect) - metoprolol (oral/iv)
34
why should beta blockers be avoided for patients with asthma or cardiac issues
- beta 2 affects the airways and arteries - beta 1 affects heart
35
what med is used to increase heart rate, when is it used
adenosine (vasodilator) - used in myocardial stress perfusion (weight base diffusion with ECG monitoring, not bolus)
36
how does adenosine work
diseased artery won't be able to dilate so differential perfusion seen in myocardium
37
caffeine blocks adenosine so should be abstained before prescription
38
what form of adenosine is used in nuclear medicine
regadenoson - fixed dose - fewer side effects - reversible
39
what node is blocked by adenosine to slow heart rate
atrial ventricular
40
besides adenosine, what other drug is used giving similar effects. State its characteristics and whats it good for seeing
dobutamine (I CMR, NM, ECHO) - beta 1 agonist (heart) - POSITIVE inotropic effect (increase heart contractility) - increases blood perfusion so can see iscaemia in perfusion imaging - good for evaluating wall motion (iscaemic myocardium cant function as well so wall abnormality seen)
41
what is a diuretic and what drug is commonly used for this
increases urine production - FUROSEMIDE
42
Why is furosemide used (diuretic)
accentuate appearance of renal tract obstruction / urinary excretion contrast helps visualise renal tract - more pee/waste = increase contrast = better images
43
Emergency drugs are used for what reaction : adrenaline, amiodarone, atropine, salbutamol, aminophylline, flumazenil, naloxone, steroids, antihistamines
- anaphylaxis - heart arythmya - brings heart rate back uo - bronchial spams/ breathing - hard core asthma drug - blocks effects of opiods - inflammation e.g severe allergy - light allergy rreaction