control of metabolic pathways 2.1 Flashcards
(18 cards)
what controls metabolic pathways
the prescence ot absence of enzymes
do substrates have a high or low affinity to the active site
high
to products have a high or low affinity to the active site
low allowing them to leave the active site
what is induced fit
induced fit is when the active site doesnt perfectly fit the substrate but molds to its shape this makes for a tight fit and the reaction is more likely to take place
what is the energy required for a chemical reaction called
activarion energy
what do enzymes do to the activation energy
lower it
what effects the rate of an enzyme controlled reaction
the concentration of substrate and end product
as the substrate concentration increases, the rate of enzyme activity increases until…
all active sites are taken
what drives reversable reaxtions in a particular direction
the prescence of a substrate or removal of a product
what changes the rate of an enzyme catalised reaction
concentration of substrates relative to concentration of products
what are the types of inhibition
competative
non competative
feedback inhibition
describe competative inhibition
inhibitor competes for the active site of the enzyme
is competative inhibition reversable
yes
by increasing substrate concentration it is more likely to bind to the active site
describe non competatibe inhibition
bind to another site on the enzyme and perminently change the shape of the enzyme
can noncompetative inhibition be reversed by increasing substrate concentration
no its permanent
describe feedback inhibition
when the end product in a metabolic pathway inhibits an enzyme earlier in the pathway
what is the role of genes in metabolic pathways
genes code for the enzymes that control the metabolic pathways genes code for amino acids and the series of bases controls the shape size and function of an enzyme.
describe the effect on the increase in substrate concentration on the direction and soeed of n enzyme controlled reaction
sends reaction in direction of end product and speeds up the rate of reaction
